(E)-2-Diazonio-1-(3,4,5-trimethoxyphenyl)ethen-1-olate

Base Information

• Chemical Name: (E)-2-Diazonio-1-(3,4,5-trimethoxyphenyl)ethen-1-olate
• CAS No.: 7702-09-2
• Molecular Formula: C11H12 N2 O4
• Molecular Weight: 236.227
• NSC Number: 55354
• DSSTox Substance ID: DTXSID20713266
• Nikkaji Number: J2.570.245J
• Wikidata: Q82649519
• Mol file: 7702-09-2.mol

Synonyms:7702-09-2;DTXSID20713266;NSC55354;NSC-55354;alpha-Diazo-3',4',5'-trimethoxyacetophenone;(E)-2-Diazonio-1-(3,4,5-trimethoxyphenyl)ethen-1-olate

Chemical Property of (E)-2-Diazonio-1-(3,4,5-trimethoxyphenyl)ethen-1-olate

Chemical Property:

• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 5
• Exact Mass: 236.07970687
• Heavy Atom Count: 17
• Complexity: 301

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COC1=CC(=CC(=C1OC)OC)C(=O)C=[N+]=[N-]

Technology Process of (E)-2-Diazonio-1-(3,4,5-trimethoxyphenyl)ethen-1-olate

There total 4 articles about (E)-2-Diazonio-1-(3,4,5-trimethoxyphenyl)ethen-1-olate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

1,3-di-(3,4,5-trimethoxyphenyl)-1,3-propanedione (93199-59-8) → 2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone (7702-09-2)

Guidance literature:

With 4-toluenesulfonyl azide; methylamine; In ethanol; at 20 ℃; for 2h;

Reference yield: 85.0%

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3,4,5-Trimethoxybenzoyl chloride (4521-61-3) → 2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone (7702-09-2)

Guidance literature:

In diethyl ether; at 0 - 20 ℃;

DOI:10.1071/CH03133

Reference yield:

3,4,5-Trimethoxybenzoyl chloride (4521-61-3) + diazomethyl-trimethyl-silane (18107-18-1) → 2-diazo-1-(3,4,5-trimethoxyphenyl)ethanone (7702-09-2)

Guidance literature:

3,4,5-Trimethoxybenzoyl chloride; diazomethyl-trimethyl-silane; In diethyl ether; 1,2-dichloro-ethane; at 20 ℃;

With polymer-supported fluoride; In diethyl ether; 1,2-dichloro-ethane; for 0.7h;

DOI:10.1021/ol1027927

upstream raw materials:

diazomethane

3,4,5-Trimethoxybenzoyl chloride

Eudesmic acid

diazomethyl-trimethyl-silane

Downstream raw materials:

2-(3,4,5-trimethoxyphenyl)acetamide

N-methyl-3,4,5-trimethoxyphenethylamine

7-methyl-2-(3,4,5-trimethoxyphenyl)quinoxaline

C₁₈H₁₈N₂O₃