2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride

Base Information

• Chemical Name: 2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride
• CAS No.: 6579-27-7
• Molecular Formula: C7H4Cl3NO
• Molecular Weight: 224.474
• Hs Code.: 2925290090
• European Community (EC) Number: 815-144-7
• Mol file: 6579-27-7.mol

Synonyms:6579-27-7;2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride;2,6-Dichloro-N-hydroxybenzimidoyl chloride;(Z)-2,6-dichloro-N-hydroxybenzene-1-carbonimidoyl chloride;(Z)-2,6-dichloro-N-hydroxybenzimidoyl chloride;(1Z)-2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride;1782938-75-3;(E)-2,6-dichloro-N-hydroxybenzimidoyl chloride;SCHEMBL1106341;35623-69-9;CS-M0367;STR09346;MFCD00221426;ZB1453;AM20040967;2,6-Dichloro-N-hydroxybenzene-carboximidoyl chloride;A1-36658;F2163-0263

Chemical Property of 2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride

Chemical Property:

• Vapor Pressure: 1.79E-05mmHg at 25°C
• Melting Point: 85 °C
• Refractive Index: 1.597
• Boiling Point: 349.187 °C at 760 mmHg
• PKA: 9.77±0.70(Predicted)
• Flash Point: 164.983 °C
• PSA: 32.59000
• Density: 1.531g/cm³
• LogP: 3.36800
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 222.935847
• Heavy Atom Count: 12
• Complexity: 176

Purity/Quality:

97% ^*data from raw suppliers

2,6-dichloro-α-chlorobenzaldoxime ^*data from reagent suppliers

Safty Information:

• Pictogram(s): C
• Hazard Codes: C

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)C(=NO)Cl)Cl
• Isomeric SMILES: C1=CC(=C(C(=C1)Cl)/C(=N/O)/Cl)Cl

Technology Process of 2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride

There total 9 articles about 2,6-dichloro-N-hydroxybenzenecarboximidoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2,6-dichlorobenzaldoxime (25185-95-9) → 2,6-dichlorobenzohydroximoyl chloride (6579-27-7)

Guidance literature:

With hydrogenchloride; potassium peroxomonosulfate; In N,N-dimethyl-formamide; for 8h; Ambient temperature;

DOI:10.1021/jo00050a054

Reference yield: 97.0%

(1E)-2,6-dichlorobenzaldehyde oxime (6575-28-6) → 2,6-Dichloro-N-hydroxybenzenecarboximidoyl chloride (6579-27-7)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 20 ℃; for 2h;

DOI:10.1002/cmdc.201500136

Reference yield: 73.0%

2,6-dichlorobenzaldehyde (83-38-5) → 2,6-dichlorobenzohydroximoyl chloride (6579-27-7)

Guidance literature:

2,6-dichlorobenzaldehyde; With hydroxylamine hydrochloride; potassium carbonate; In ethanol; water; at 0 - 90 ℃; for 2h;

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 0 ℃;

upstream raw materials:

2,6-dichlorobenzaldoxime

2,6-dichlorobenzaldehyde

(1E)-2,6-dichlorobenzaldehyde oxime

2,6-dichlorobenzaldoxime

Downstream raw materials:

methyl 3-(2,6-dichlorophenyl)-4-acetylisoxazole-5-carboxylate

3-(2,6-Dichloro-phenyl)-4-(4-nitro-phenyl)-5-trifluoromethyl-isoxazole

3-(2,6-Dichloro-phenyl)-5-(4-nitro-phenyl)-4-trifluoromethyl-isoxazole