methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

Base Information

Chemical Name:methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate
CAS No.:953040-34-1
Molecular Formula:C₁₉H₁₉N₃O₃S₂
Molecular Weight:401.51
Hs Code.:

Synonyms:methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

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Chemical Property of methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

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Technology Process of methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

There total 1 articles about methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.5%

: 2935-90-2
Methyl 3-mercaptopropionate

: 953040-28-3
5-bromo-N-(4-methylthiazol-2-yl)-3-phenoxypyridin-2-amine

: 953040-34-1
methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; In 1,4-dioxane; at 100 ℃; for 2h;

Reference yield: 60.5%

: 953040-34-1
methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

: 31106-82-8
2-(bromomethyl)pyridine hydrobromide

: 4-Methyl-N-(3-phenoxy-5-(pyridin-2-ylmethylthio)pyridin-2-yl)thiazol-2-amine dihydrochloride

Guidance literature:: methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.00833333h;

2-(bromomethyl)pyridine hydrobromide; In tetrahydrofuran; at 20 ℃; for 0.5h;

With hydrogenchloride;

Reference yield: 41.4%

: 23056-36-2
2-chloro-4-nitropyridine

: 953040-34-1
methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate

: 5-(2-chloropyridin-4-ylthio)-N-(4-methylthiazol-2-yl)-3-phenoxypyridin-2-amine dihydrochloride

Guidance literature:: 2-chloro-4-nitropyridine; methyl 3-(6-(4-methylthiazol-2-ylamino)-5-phenoxypyridin-3-ylthio)propanoate; In dimethyl sulfoxide; for 0.0833333h;

With potassium tert-butylate; In dimethyl sulfoxide; for 0.5h;