2-phenyl-1-vinylnaphthalene

Base Information

• Chemical Name: 2-phenyl-1-vinylnaphthalene
• CAS No.: 89125-95-1
• Molecular Formula: C₁₈H₁₄
• Molecular Weight: 230.309
• Mol file: 89125-95-1.mol

Synonyms:2-phenyl-1-vinylnaphthalene

Chemical Property of 2-phenyl-1-vinylnaphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-phenyl-1-vinylnaphthalene

There total 5 articles about 2-phenyl-1-vinylnaphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 43.0%

C23H24O2 → 2-phenyl-1-vinylnaphthalene (89125-95-1)

Guidance literature:

With 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide; In toluene; at 110 ℃; for 6h; chemoselective reaction; Inert atmosphere;

DOI:10.1002/adsc.201300525

Reference yield:

o-allylbenzaldehyde (62708-42-3) → 2-phenyl-1-vinylnaphthalene (89125-95-1)

Guidance literature:

Multi-step reaction with 3 steps

1.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / 0 °C

1.2: 0.17 h / 0 °C

2.1: triethylamine; dmap / dichloromethane / 0.17 h / 20 °C / Schlenk technique

3.1: 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide / toluene / 6 h / 110 °C / Inert atmosphere

With dmap; n-butyllithium; 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide; triethylamine; In tetrahydrofuran; hexane; dichloromethane; toluene;

DOI:10.1002/adsc.201300525

Reference yield:

2-formylbenzene boronic acid (40138-16-7) → 2-phenyl-1-vinylnaphthalene (89125-95-1)

Guidance literature:

Multi-step reaction with 4 steps

1.1: potassium phosphate; bis(benzonitrile)palladium(II) dichloride / N,N-dimethyl acetamide; water

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.5 h / 0 °C

2.2: 0.17 h / 0 °C

3.1: triethylamine; dmap / dichloromethane / 0.17 h / 20 °C / Schlenk technique

4.1: 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide / toluene / 6 h / 110 °C / Inert atmosphere

With dmap; potassium phosphate; bis(benzonitrile)palladium(II) dichloride; n-butyllithium; 2-(dicyclohexylphosphino)-2',4',6'-triisopropylbiphenyl Au bis(trifluoromethylsulfonyl)imide; triethylamine; In tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl acetamide; water; toluene; 1.1: |Suzuki-Miyaura Coupling;

DOI:10.1002/adsc.201300525

upstream raw materials:

methyl magnesium iodide

o-allylbenzaldehyde

2-formylbenzene boronic acid