2,4-dimethoxy-3-isopropylbenzoic acid

Base Information

• Chemical Name: 2,4-dimethoxy-3-isopropylbenzoic acid
• CAS No.: 167961-19-5
• Molecular Formula: C₁₂H₁₆O₄
• Molecular Weight: 224.257
• Mol file: 167961-19-5.mol

Synonyms:2,4-dimethoxy-3-isopropylbenzoic acid

Chemical Property of 2,4-dimethoxy-3-isopropylbenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-dimethoxy-3-isopropylbenzoic acid

There total 3 articles about 2,4-dimethoxy-3-isopropylbenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

2,4-Dimethoxy-3-isopropyl-benzaldehyde (144707-45-9) → 2,4-dimethoxy-3-isopropylbenzoic acid (167961-19-5)

Guidance literature:

With potassium permanganate; In acetone; for 16h; Ambient temperature;

DOI:10.1007/BF00807060

Reference yield:

2,4-dimethoxy-3-isopropylbenzonitrile → 2,4-dimethoxy-3-isopropylbenzoic acid (167961-19-5)

Guidance literature:

With sodium hydroxide; In ethanol; Yield given;

DOI:10.1016/00404-0399(50)11425-

Reference yield:

1,3-dimethoxy-2-(1-methylethyl)benzene (16700-61-1) → 2,4-dimethoxy-3-isopropylbenzoic acid (167961-19-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) POCl₃ / 1.) r.t., 45 min, 2.) r.t., 1 h; 60 deg C, 2 h; r.t., overnight

2: 68 percent / KMnO₄ / acetone / 16 h / Ambient temperature

With potassium permanganate; trichlorophosphate; In acetone;

DOI:10.1007/BF00807060

upstream raw materials:

2,4-Dimethoxy-3-isopropyl-benzaldehyde

1,3-dimethoxy-2-(1-methylethyl)benzene

Downstream raw materials:

2,4-Dimethoxy-3-isopropylbenzoic chloride

2,4-Dimethoxy-3-isopropyl-6-<(3,5-dimethoxyphenyl)-methyl>-benzoic acid

5,7-Dimethoxy-6-isopropyl-3-(3,5-dimethoxyphenyl)-3H-isobenzofuranone

2,4-Dimethoxy-3-isopropyl-N,N-diethylbenzamide