16700-61-1

Basic information

• Product Name: Benzene, 1,3-dimethoxy-2-(1-methylethyl)-
• CAS NO: 16700-61-1
• Molecular Formula: C11H16O2
• Molecular Weight: 180.247
• Mol File: 16700-61-1.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzene, 1,3-dimethoxy-2-(1-methylethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1,3-dimethoxy-2-(1-methylethyl)-(16700-61-1)
• EPA Substance Registry System: Benzene, 1,3-dimethoxy-2-(1-methylethyl)-(16700-61-1)

Safety Data

• Hazardous Substances Data: 16700-61-1(Hazardous Substances Data)

Upstream product

• 151-10-0 1,3-Dimethoxybenzene 
• 80041-89-0 isopropylboronic acid 
• 16932-45-9 1-bromo-2,6-dimethoxybenzene 
• 699-83-2 2,6-dihydroxylacetophenone 
• 2040-04-2 2,6-dimethoxyacetophenone 
• 2065-27-2 methyl 2,6-dimethoxybenzoate 
• 16929-70-7 1,3-dimethoxy-2-(1-hydroxy-1-methylethyl)benzene 
• 25108-61-6 1,3-dimethoxy-2-(1-methylethenyl)benzene 

Downstream Products

• 62858-83-7 2-isopropylbenzene-1,3-diol 
• 82961-07-7 4-(2,4-dimethoxy-3-isopropylphenyl)4-oxobutyric acid 
• 82961-10-2 4-(2,4-dimethoxy-3-isopropylphenyl)butanoic acid 
• 60241-78-3 3-(1-methylethyl)-1,2,4-trimethoxybenzene 
• 144707-47-1 2,4-Dimethoxy-3-isopropylbenzyl bromide 
• 144707-46-0 2,4-Dimethoxy-3-isopropylbenzyl alcohol 
• 144707-45-9 2,4-Dimethoxy-3-isopropyl-benzaldehyde 
• 144707-49-3 2,4-Dimethoxy-3-isopropylphenylacetonitrile 
• 144707-31-3 7-Cyano-3-phenylthio-12,14-dimethoxyabieta-8,11,13-triene 
• 144707-54-0 Trifluoro-acetic acid (4aR,10aS)-7-isopropyl-6,8-dimethoxy-1,1,4a-trimethyl-2-phenylsulfanyl-1,4,4a,10a-tetrahydro-phenanthren-9-yl ester 
• 1305339-26-7 2-(4-isopropyl-3,5-dimethoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane 
• 123151-45-1 3-methoxy-2-(1-methylethyl)phenol 

Relevant articles and documents

ISOQUINOLINE COMPOUNDS AND THEIR USE IN TREATING AhR IMBALANCE

The present invention is directed to novel compounds of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof. Pharmaceutical compositions comprising a compound of Formula (I), or a pharmaceutically acceptable salt, solvate or hydrate thereof, are also described. The invention is also directed to use of the compounds of Formula (I) for treating a condition in a mammal associated with AhR imbalance, such as an inflammatory disease or disorder.

SUBSTITUTED-N-HETEROARYL COMPOUNDS AND USES THEREOF

The present disclosure relates generally to compounds useful for the treatment and/or enhancement of cognitive function and negative symptoms associated with central nervous system disorders where the circuitry involving fast spiking PV+ interneurons and the production of cortical gamma oscillations is disrupted. The subject disclosure enables the manufacture of medicaments as well as compositions containing same for use in methods of therapy and prophylaxis of cognitive dysfunction and negative symptoms.

Efficient synthesis of sterically hindered arenes bearing acyclic secondary alkyl groups by suzuki-miyaura cross-couplings

Bulky P,P-O ligands were designed to inhibit isomerization and reduction side reactions during the cross coupling between sterically hindered aryl halides and alkylboronic acids. Suzuki-Miyaura cross-couplings between di-ortho-substituted aryl bromides and acyclic secondary alkylboronic acids have been achieved with high yields. The method has also enabled the preparation of ortho-alkoxy di-ortho-substituted arenes bearing isopropyl groups in excellent yields. The utility of the synthetic method has been demonstrated in a late-stage modification of estrone and in the application to a new synthetic route toward gossypol. No side reaction: The shown bulky P,P-O ligands (right) successfully inhibit isomerization and reduction side reactions of the cross-coupling of sterically hindered substrates such as di-ortho-substituted aryl bromides with acyclic secondary alkylboronic acids. The method also allows the preparation of ortho-alkoxy di-ortho-substituted isopropyl arenes in excellent yields.