Technology Process of 2,4-Dimethoxy-3-isopropylbenzoic chloride
There total 2 articles about 2,4-Dimethoxy-3-isopropylbenzoic chloride which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) POCl3 / 1.) r.t., 45 min, 2.) r.t., 1 h; 60 deg C, 2 h; r.t., overnight
2: 68 percent / KMnO4 / acetone / 16 h / Ambient temperature
3: SOCl2 / benzene / 2.5 h / Heating
With
potassium permanganate; thionyl chloride; trichlorophosphate;
In
acetone; benzene;
DOI:10.1007/BF00807060
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diethyl ether / 0.25 h
2: 40 percent / TMEDA, tert-butyl lithium / tetrahydrofuran / 1.) -80 deg C, 15 min, 2.) -80 deg C, 2 h
3: 86 percent / H2 / 10percent Pd/C / acetic acid / 3 h / 65 - 70 °C / 750.06 Torr
With
N,N,N,N,-tetramethylethylenediamine; hydrogen; tert.-butyl lithium;
palladium on activated charcoal;
In
tetrahydrofuran; diethyl ether; acetic acid;
DOI:10.1007/BF00807060
