Quinine hydrochloride

Base Information Edit

Chemical Name:Quinine hydrochloride
CAS No.:130-89-2
Deprecated CAS:11034-23-4,70181-37-2,70181-38-3,918656-55-0,70181-37-2,70181-38-3,918656-55-0
Molecular Formula:C₂₀H₂₄N₂O₂*ClH
Molecular Weight:360.884
Hs Code.:29392000
European Community (EC) Number:231-437-7,205-001-1,612-097-2
UNII:7CS0WNO31M
DSSTox Substance ID:DTXSID7044213
Wikidata:Q27268091
NCI Thesaurus Code:C90739
ChEMBL ID:CHEMBL588046
Mol file:130-89-2.mol

Synonyms:Biquinate;Bisulfate, Quinine;Hydrochloride, Quinine;Legatrim;Myoquin;Quinamm;Quinbisan;Quinbisul;Quindan;Quinimax;Quinine;Quinine Bisulfate;Quinine Hydrochloride;Quinine Lafran;Quinine Sulfate;Quinine Sulphate;Quinine-Odan;Quinoctal;Quinson;Quinsul;Strema;Sulfate, Quinine;Sulphate, Quinine;Surquina

Suppliers and Price of Quinine hydrochloride

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Quinine hydrochloride
50mg
$ 267.00

TRC
QuinineHydrochloride
50mg
$ 45.00

Tocris
Quininehydrochloride
50
$ 53.00

Crysdot
(R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanolhydrochloride 97%
500g
$ 336.00

Chemenu
(R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanolhydrochloride 97%
500g
$ 315.00

American Custom Chemicals Corporation
QUININE HYDROCHLORIDE 95.00%
10G
$ 179.55

American Custom Chemicals Corporation
QUININE HYDROCHLORIDE 95.00%
50G
$ 2710.50

Ambeed
(R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanolhydrochloride 99%mixTBCasstabilizer
500g
$ 495.00

Ambeed
(R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanolhydrochloride 99%mixTBCasstabilizer
100g
$ 135.00

Ambeed
(R)-(6-Methoxyquinolin-4-yl)((1S,2S,4S,5R)-5-vinylquinuclidin-2-yl)methanolhydrochloride 99%mixTBCasstabilizer
5g
$ 11.00

Total 92 raw suppliers

Chemical Property of Quinine hydrochloride Edit

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:158-160 °C
Refractive Index:1.638
Boiling Point:495.9 °C at 760 mmHg
Flash Point:253.7 °C
PSA：45.59000
Density:1.21 g/cm³
LogP:3.91310
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Solubility.:DMSO (Slightly), Ethanol (1g/1ml), glycerol(1g/7ml), chloroform(1g/1ml)
Water Solubility.:549.7mg/L(25 oC)
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:360.1604557
Heavy Atom Count:25
Complexity:457

Purity/Quality:

99% ^*data from raw suppliers

Quinine hydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=CN=C2C=C1)C(C3CC4CCN3CC4C=C)O.Cl
Isomeric SMILES:COC1=CC2=C(C=CN=C2C=C1)[C@H]([C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)O.Cl
Recent ClinicalTrials:Effect of Quinine Hydrochloride in Overweight Population on Food Intake, Hunger and Gut Peptide Release
Recent NIPH Clinical Trials:The Effect of Quinine Hydrochloride on Pain after Hemorrhoidectomy
Uses Quinine Hydrochloride is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.

Technology Process of Quinine hydrochloride

There total 4 articles about Quinine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: