(S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Base Information

Chemical Name:(S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate
CAS No.:935548-40-6
Molecular Formula:C₃₇H₅₉N₂O₇P
Molecular Weight:674.858
Hs Code.:

Synonyms:(S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Suppliers and Price of (S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

There total 4 articles about (S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 935548-22-4
(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

: 756-79-6
dimethyl methane phosphonate

: 935548-40-6
(S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Guidance literature:: dimethyl methane phosphonate; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 0.25h; Inert atmosphere;

(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate; In tetrahydrofuran; at -78 ℃; for 0.333333h; Inert atmosphere;
DOI:10.1016/j.bmcl.2010.09.030

Reference yield:

: 3417-91-2
L-tyrosine methyl ester HCl

: 935548-40-6
(S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: Et₃N / CH₂Cl₂ / 3 h / 0 °C

2.1: K₂CO₃; 18-crown-6 / acetone / Heating

3.1: n-BuLi

3.2: 3 h / -78 °C

With n-butyllithium; 18-crown-6 ether; potassium carbonate; triethylamine; In dichloromethane; acetone;
DOI:10.1016/j.bmcl.2006.12.114

Reference yield:

: 112-67-4
n-hexadecanoyl chloride

: 935548-40-6
(S)-dimethyl 4-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-oxo-3-palmitamidobutylphosphonate

Guidance literature:: Multi-step reaction with 3 steps

1.1: Et₃N / CH₂Cl₂ / 3 h / 0 °C

2.1: K₂CO₃; 18-crown-6 / acetone / Heating

3.1: n-BuLi

3.2: 3 h / -78 °C

With n-butyllithium; 18-crown-6 ether; potassium carbonate; triethylamine; In dichloromethane; acetone;
DOI:10.1016/j.bmcl.2006.12.114