(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

Base Information

Chemical Name:(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate
CAS No.:935548-22-4
Molecular Formula:C₃₅H₅₄N₂O₅
Molecular Weight:582.824
Hs Code.:

Synonyms:(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

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Chemical Property of (S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

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Technology Process of (S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

There total 3 articles about (S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 477585-18-5
methanesulfonic acid 4-methoxy-3,5-dimethyl-pyridin-2-ylmethyl ester

: 214706-38-4
(S)-methyl 3-(4-hydroxyphenyl)-2-(palmitamido)propanoate

: 935548-22-4
(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

Guidance literature:: With 18-crown-6 ether; potassium carbonate; In acetone; Heating;
DOI:10.1016/j.bmcl.2006.12.114

Reference yield:

: 3417-91-2
L-tyrosine methyl ester HCl

: 935548-22-4
(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 3 h / 0 °C

2: K₂CO₃; 18-crown-6 / acetone / Heating

With 18-crown-6 ether; potassium carbonate; triethylamine; In dichloromethane; acetone;
DOI:10.1016/j.bmcl.2006.12.114

Reference yield:

: 112-67-4
n-hexadecanoyl chloride

: 935548-22-4
(S)-methyl 3-(4-((4-methoxy-3,5-dimethylpyridin-2-yl)methoxy)phenyl)-2-palmitamidopropanoate

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / 3 h / 0 °C

2: K₂CO₃; 18-crown-6 / acetone / Heating

With 18-crown-6 ether; potassium carbonate; triethylamine; In dichloromethane; acetone;
DOI:10.1016/j.bmcl.2006.12.114