1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Base Information

Chemical Name:1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate
CAS No.:128576-61-4
Molecular Formula:C₃₅H₃₅NO₄
Molecular Weight:533.667
Hs Code.:

Synonyms:1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Suppliers and Price of 1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

There total 5 articles about 1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 55135-66-5
9-bromo-9-phenyl-9H-fluorene

: 128576-60-3
1-tert-butyl 4-methyl (2S)-2-(benzylamino)butanedioate

: 128576-61-4
1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Guidance literature:: With potassium phosphate; lead(II) nitrate; In acetonitrile; for 16h; Ambient temperature;
DOI:10.1021/jo00304a011

Reference yield:

: 100-52-7
benzaldehyde

: 128576-61-4
1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Guidance literature:: Multi-step reaction with 2 steps

1: 1) 10percent Pd/C, H₂; 2) sodium cyanoborohydride / 1) methanol, acetic acid, RT, 1 atm, 16 h; 2) RT, 30 min, then 0 deg C, 15 min

2: 92 percent / Pb(NO₃)2, K₃PO₄ / acetonitrile / 16 h / Ambient temperature

With potassium phosphate; palladium on activated charcoal; lead(II) nitrate; hydrogen; sodium cyanoborohydride; In acetonitrile;
DOI:10.1021/jo00304a011

Reference yield:

: 104072-49-3
L-aspartic acid α-t-butyl β-methyl diester

: 128576-61-4
1-(tert-butyl) 4-methyl N-benzyl-N-(9-phenyl-9H-fluoren-9-yl)-L-aspartate

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / methanol / 2 h / 20 °C

1.2: 1 h / 0 °C

2.1: lead(II) nitrate; potassium phosphate / acetonitrile / 2 h / 20 °C

With potassium phosphate; lead(II) nitrate; acetic acid; In methanol; acetonitrile;