Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester

Base Information

• Chemical Name: Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester
• CAS No.: 157992-81-9
• Molecular Formula: C₂₈H₃₀O₃S₃
• Molecular Weight: 510.742
• Mol file: 157992-81-9.mol

Synonyms:Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester

Chemical Property of Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester

There total 4 articles about Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bromoacetic acid tert-butyl ester (5292-43-3) → Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester (157992-81-9)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / Bu₄NHSO₄, 40percent NaOH / benzene; H₂O

2: 93 percent / Et₃B / toluene / 22 °C

3: 1.) LiHMDS / 1.) Et₂O, -78 deg C; 2.) Et₂O, 22 deg C

With sodium hydroxide; triethyl borane; tetra(n-butyl)ammonium hydrogensulfate; lithium hexamethyldisilazane; In water; toluene; benzene;

DOI:10.1016/S0040-4039(00)78198-6

Reference yield:

thiophenol (108-98-5) → Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester (157992-81-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / Et₃B / toluene / 22 °C

2: 1.) LiHMDS / 1.) Et₂O, -78 deg C; 2.) Et₂O, 22 deg C

With triethyl borane; lithium hexamethyldisilazane; In toluene;

DOI:10.1016/S0040-4039(00)78198-6

Reference yield:

tert-butyl 2-(but-3-yn-1-yloxy)acetate (157992-79-5) → Bis-phenylsulfanyl-((E)-4-phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester (157992-81-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 93 percent / Et₃B / toluene / 22 °C

2: 1.) LiHMDS / 1.) Et₂O, -78 deg C; 2.) Et₂O, 22 deg C

With triethyl borane; lithium hexamethyldisilazane; In toluene;

DOI:10.1016/S0040-4039(00)78198-6

upstream raw materials:

diphenyldisulfane

((E)-4-Phenylsulfanyl-but-3-enyloxy)-acetic acid tert-butyl ester

bromoacetic acid tert-butyl ester

thiophenol