ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate

Base Information

• Chemical Name: ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate
• CAS No.: 960127-75-7
• Molecular Formula: C₁₃H₁₄O₂
• Molecular Weight: 202.253
• Mol file: 960127-75-7.mol

Synonyms:ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate

Chemical Property of ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate

There total 1 articles about ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diazoacetic acid ethyl ester (623-73-4) + 1-indene (95-13-6) → (+/-)-trans-1,1a,6,6a-tetrahydro-cyclopropa[a]indene-1-carboxylic acid ethyl ester + ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate (960127-75-7) + diethyl Fumarate (623-91-6) + Diethyl maleate (141-05-9)

Guidance literature:

With Na₁₀[Bi₂W₂₀O₇₀Co₂(H₂O)6]; In 1,2-dichloro-ethane; at 75 ℃; for 1.66667h; optical yield given as %de; Inert atmosphere;

DOI:10.1002/adsc.201000378

Reference yield:

ethyl (1S,1aR,6aS)-1,1a,6,6a-tetrahydrocyclopropa[a]indene-1-carboxylate (960127-75-7) + (S)-4-phenyl-2-oxazolidinone (99395-88-7,7480-32-2) → C20H17NO3

Guidance literature:

With dmap; pivaloyl chloride; triethylamine; In tetrahydrofuran; at -78 ℃; for 5h; Inert atmosphere;

DOI:10.1016/j.ejmech.2017.09.073

upstream raw materials:

diazoacetic acid ethyl ester

1-indene