2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE

Base Information

Chemical Name:2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE
CAS No.:101664-56-6
Molecular Formula:C5H2ClFN2O3
Molecular Weight:192.534
Hs Code.:2933399090
DSSTox Substance ID:DTXSID40426821
Wikidata:Q72451015
Mol file:101664-56-6.mol

Synonyms:2-chloro-3-fluoro-4-nitropyridin-1-ol;2-Chloro-3-fluoro-4-nitropyridine-n-oxide;2-chloro-3-fluoro-4-nitropyridine 1-oxide;2-Chlor-3-fluor-4-nitropyridin-1-oxid;

Suppliers and Price of 2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
2-Chloro-3-fluoro-4-nitropyridine 1-oxide 95%
250mg
$ 260.00

Matrix Scientific
2-Chloro-3-fluoro-4-nitropyridine 1-oxide 95%
1g
$ 785.00

Labseeker
2-Chloro-3-fluoro-4-nitropyridine-N-oxide 95
10g
$ 1500.00

Labseeker
2-Chloro-3-fluoro-4-nitropyridine-N-oxide 95
5g
$ 1100.00

Labseeker
2-Chloro-3-fluoro-4-nitropyridine-N-oxide 95
1g
$ 750.00

Biosynth Carbosynth
2-chloro-3-fluoro-4-nitro-1-oxidopyridin-1-ium
1 g
$ 350.00

Biosynth Carbosynth
2-chloro-3-fluoro-4-nitro-1-oxidopyridin-1-ium
500 mg
$ 225.00

Biosynth Carbosynth
2-chloro-3-fluoro-4-nitro-1-oxidopyridin-1-ium
250 mg
$ 125.00

Biosynth Carbosynth
2-chloro-3-fluoro-4-nitro-1-oxidopyridin-1-ium
100 mg
$ 80.00

Biosynth Carbosynth
2-chloro-3-fluoro-4-nitro-1-oxidopyridin-1-ium
50 mg
$ 50.00

Total 26 raw suppliers

Chemical Property of 2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Melting Point:176-178 °C
Refractive Index:1.606
Boiling Point:428.758 °C at 760 mmHg
PKA:-3.24±0.10(Predicted)
Flash Point:213.106 °C
PSA：71.28000
Density:1.748 g/cm³
LogP:2.33900
Water Solubility.:Insoluble in water.
XLogP3:0.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:0
Exact Mass:191.9737978
Heavy Atom Count:12
Complexity:188

Purity/Quality:

99% ^*data from raw suppliers

2-Chloro-3-fluoro-4-nitropyridine 1-oxide 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s): R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system a
Hazard Codes:R23/24/25:Toxic by inhalation, in contact with skin and if swallowed.; R36/37/38:Irritating to eyes, respiratory system a
Statements: 23/24/25-36/37/38
Safety Statements: 22-26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C[N+](=C(C(=C1[N+](=O)[O-])F)Cl)[O-]
Uses It is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff.

Technology Process of 2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE

There total 4 articles about 2-CHLORO-3-FLUORO-4-NITROPYRIDINE N-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 2.2%

: 85386-94-3
2-Chlor-3-fluorpyridin-1-oxid

: 101664-60-2
2-chloro-3-fluoro-6-nitro-pyridine-N-oxide

: 101664-56-6
2-Chlor-3-fluor-4-nitropyridin-1-oxid

Guidance literature:: With sulfuric acid; sulfur trioxide; nitric acid; for 1h; Heating;

Reference yield:

: 17282-04-1
2-chloro-3-fluoropyridine

: 101664-56-6
2-Chlor-3-fluor-4-nitropyridin-1-oxid

Guidance literature:: Multi-step reaction with 2 steps

1: 64 percent / (CH₃CO)2O, 30percent H₂O₂ / 12 h / 80 °C

2: 44 percent / conc. H₂SO₄/H₂SO₄ (20percent SO₃) (1:1); H₂SO₄ (20percent SO₃)/100percent HNO₃ / 1 h / Heating

With sulfuric acid; sulfur trioxide; dihydrogen peroxide; nitric acid; acetic anhydride;

Reference yield:

: 462-08-8
pyridin-3-ylamine

: 101664-56-6
2-Chlor-3-fluor-4-nitropyridin-1-oxid

Guidance literature:: Multi-step reaction with 4 steps

1: 82 percent / 15percent H₂O₂, conc. HCl

2: 38 percent

3: 54 percent / acetic anhydride, 30percent H₂O₂

4: 42 percent / 100percent HNO₃/ 100percent H₂SO₄ containing 10percent SO₃

With hydrogenchloride; sulfuric acid; sulfur trioxide; dihydrogen peroxide; nitric acid; acetic anhydride;
DOI:10.1016/S0040-4039(00)94981-5