1-(Benzyloxy)-3-iodobenzene

Base Information

• Chemical Name: 1-(Benzyloxy)-3-iodobenzene
• CAS No.: 107623-21-2
• Molecular Formula: C13H11IO
• Molecular Weight: 310.134
• Hs Code.: 2909309090
• European Community (EC) Number: 926-005-6,626-393-4
• DSSTox Substance ID: DTXSID20401035
• Nikkaji Number: J1.003.030G
• Mol file: 107623-21-2.mol

Synonyms:1-(Benzyloxy)-3-iodobenzene;107623-21-2;3-Iodobenzyloxybenzene;1-Benzyloxy-3-Iodobenzene;1-iodo-3-phenylmethoxybenzene;1-Benzyloxy-3-iodo-benzene;Benzene, 1-iodo-3-(phenylmethoxy)-;C13H11IO;3-Benzyloxyiodobenzene;3-Iodobenzyloxybenzene, 90%;SCHEMBL314468;benzyl-(3-iodo-phenyl)-ether;DTXSID20401035;QMKHOPJXDQAHBG-UHFFFAOYSA-N;MFCD01318100;AKOS008912391;AS-59108;B4689;CS-0315294;FT-0607410;W12070;A801732;J-001988

Chemical Property of 1-(Benzyloxy)-3-iodobenzene

Chemical Property:

• Appearance/Colour: solid
• Vapor Pressure: 2.49E-05mmHg at 25°C
• Melting Point: 47-50 °C(lit.)
• Refractive Index: 1.635
• Boiling Point: 369.7 °C at 760 mmHg
• Flash Point: 177.4 °C
• PSA: 9.23000
• Density: 1.58 g/cm³
• LogP: 3.87020
• Storage Temp.: 2-8°C
• Sensitive.: Light Sensitive
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 309.98546
• Heavy Atom Count: 15
• Complexity: 177

Purity/Quality:

97% ^*data from raw suppliers

1-(Benzyloxy)-3-iodobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)COC2=CC(=CC=C2)I

Technology Process of 1-(Benzyloxy)-3-iodobenzene

There total 7 articles about 1-(Benzyloxy)-3-iodobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

3-Iodophenol (626-02-8) + benzyl bromide (100-39-0) → 1-(benzyloxy)-3-iodobenzene (107623-21-2)

Guidance literature:

With potassium carbonate; In acetone; at 20 ℃; for 6h; Inert atmosphere;

DOI:10.1055/s-0036-1588322

Reference yield: 99.0%

3-Iodophenol (626-02-8) → 1-(benzyloxy)-3-iodobenzene (107623-21-2)

Guidance literature:

With sodium hydride; In tetrahydrofuran;

Reference yield: 99.0%

→ 1-(benzyloxy)-3-iodobenzene (107623-21-2)

Guidance literature:

With caesium carbonate; In acetonitrile; at 80 - 85 ℃; for 2h;

upstream raw materials:

3-Iodophenol

benzyl chloride

m-iodonitrobenzene

benzyl alcohol

Downstream raw materials:

(benzyloxy)benzene

1-propyl-3-(3-(benzyloxy)phenyl)-1,2,3,6-tetrahydropyridine

3'-Benzyloxy-4-methoxybiphenyl

1-Benzyloxy-3-(4-tert-butyl-cyclohexyloxy)-benzene