acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Base Information

Chemical Name:acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside
CAS No.:191097-79-7
Molecular Formula:C₅₂H₅₂N₂O₈
Molecular Weight:832.993
Hs Code.:

Synonyms:acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Suppliers and Price of acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

There total 4 articles about acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 506-96-7
Acetyl bromide

: 191097-62-8
3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranose

: 191097-79-7
acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Guidance literature:: With sodium hydride; In N,N-dimethyl-formamide; at 0 ℃; for 0.5h;
DOI:10.1080/07328309708006530

Reference yield:

: 615-15-6
2-Methyl-1H-benzimidazole

: 191097-79-7
acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: 80 percent / acetonitrile / 3 h / Heating

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -85 °C

2.2: 91 percent / tetrahydrofuran; hexane / 0.5 h / -85 °C

3.1: 93 percent / sodium hydride / dimethylformamide / 0.5 h / 0 °C

With n-butyllithium; sodium hydride; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; acetonitrile; 1.1: Alkylation / 2.1: Metallation / 2.2: Addition / 3.1: Acetylation;
DOI:10.1080/07328309708006530

Reference yield:

: 3587-60-8
Benzyloxymethyl chloride

: 191097-79-7
acetyl-3,4,5,7-tetra-O-benzyl-1-[2-(1-benzyloxymethyl)benzimidazolyl]-1-deoxy-α-D-gluco-2-heptulopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: 80 percent / acetonitrile / 3 h / Heating

2.1: n-butyllithium / tetrahydrofuran; hexane / 0.33 h / -85 °C

2.2: 91 percent / tetrahydrofuran; hexane / 0.5 h / -85 °C

3.1: 93 percent / sodium hydride / dimethylformamide / 0.5 h / 0 °C

With n-butyllithium; sodium hydride; In tetrahydrofuran; hexane; N,N-dimethyl-formamide; acetonitrile; 1.1: Alkylation / 2.1: Metallation / 2.2: Addition / 3.1: Acetylation;
DOI:10.1080/07328309708006530