2-Fluoro-5-iodobenzoyl chloride

Base Information

Chemical Name:2-Fluoro-5-iodobenzoyl chloride
CAS No.:186584-73-6
Molecular Formula:C7H3ClFIO
Molecular Weight:284.456
Hs Code.:29163990
European Community (EC) Number:625-781-0
DSSTox Substance ID:DTXSID60380810
Wikidata:Q82171280
Mol file:186584-73-6.mol

Synonyms:2-Fluoro-5-iodobenzoyl chloride;186584-73-6;2-fluoro-5-iodobenzoylchloride;2-fluoro-5-iodo-benzoyl chloride;MFCD03094145;Benzoyl chloride, 2-fluoro-5-iodo-;SCHEMBL1306850;DTXSID60380810;CEMYZMDITJKYDA-UHFFFAOYSA-N;AKOS015912404;2-Fluoro-5-iodobenzoyl chloride, 97%;BS-15728;FT-0612357;D83910;A813059;J-011983

Suppliers and Price of 2-Fluoro-5-iodobenzoyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

SynQuest Laboratories
2-Fluoro-5-iodobenzoyl chloride
1 g
$ 61.00

SynQuest Laboratories
2-Fluoro-5-iodobenzoyl chloride
5 g
$ 141.00

SynQuest Laboratories
2-Fluoro-5-iodobenzoyl chloride
25 g
$ 376.00

Sigma-Aldrich
2-Fluoro-5-iodobenzoyl chloride 97%
5g
$ 103.00

Apolloscientific
2-Fluoro-5-iodobenzoyl chloride
5g
$ 128.00

Apolloscientific
2-Fluoro-5-iodobenzoyl chloride
1g
$ 56.00

Apolloscientific
2-Fluoro-5-iodobenzoyl chloride
25g
$ 341.00

American Custom Chemicals Corporation
2-FLUORO-5-IODOBENZOYL CHLORIDE 95.00%
10G
$ 1368.68

American Custom Chemicals Corporation
2-FLUORO-5-IODOBENZOYL CHLORIDE 95.00%
5G
$ 912.45

American Custom Chemicals Corporation
2-FLUORO-5-IODOBENZOYL CHLORIDE 95.00%
1G
$ 630.63

Total 22 raw suppliers

Chemical Property of 2-Fluoro-5-iodobenzoyl chloride

Chemical Property:

Vapor Pressure:0.00738mmHg at 25°C
Melting Point:30-34 °C(lit.)
Refractive Index:1.611
Boiling Point:269.1 °C at 760 mmHg
Flash Point:116.6 °C
PSA：17.07000
Density:2.001 g/cm³
LogP:2.80930
Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C
Sensitive.:Moisture & Light Sensitive
XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:283.89012
Heavy Atom Count:11
Complexity:165

Purity/Quality:

97% ^*data from raw suppliers

2-Fluoro-5-iodobenzoyl chloride ^*data from reagent suppliers

Safty Information:

Pictogram(s): C
Hazard Codes:C
Statements: 34
Safety Statements: 26-36/37/39-45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1I)C(=O)Cl)F
Uses Reactant for:Preparation of biologically and pharmacologically active moleculesMicrowave-assisted boron trichloride mediated coupling reactions

Technology Process of 2-Fluoro-5-iodobenzoyl chloride

There total 2 articles about 2-Fluoro-5-iodobenzoyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 124700-41-0
2-fluoro-5-iodobenzoic acid

: 186584-73-6
2-fluoro-5-iodobenzoyl chloride

Guidance literature:: With thionyl chloride; for 2h; Reflux;
DOI:10.1016/j.cclet.2013.04.047

Reference yield:

: 445-29-4
o-fluoro-benzoic acid

: 186584-73-6
2-fluoro-5-iodobenzoyl chloride

Guidance literature:: Multi-step reaction with 2 steps

1: NIS; H₂SO₄

2: SOCl₂; DMF / toluene / Heating

With N-iodo-succinimide; thionyl chloride; sulfuric acid; N,N-dimethyl-formamide; In toluene;
DOI:10.1021/jm0600139