3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Base Information

Chemical Name:3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone
CAS No.:957785-28-3
Molecular Formula:C₃₃H₃₂N₂O₇
Molecular Weight:568.626
Hs Code.:

Synonyms:3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Suppliers and Price of 3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

There total 10 articles about 3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 957785-27-2
(E)-3-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-1-[(5,6,8-trimethoxy)-2-quinolyl]-2-propen-1-one

: 71565-78-1
2-cyanopropionamide

: 957785-28-3
3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Guidance literature:: With potassium tert-butylate; In dimethyl sulfoxide; at 100 ℃; for 5h;
DOI:10.1021/jo701435p

Reference yield:

: 957785-13-6
4-chloro-5,6,8-trimethoxyquinoline-2-carboxylic acid methyl ester

: 957785-28-3
3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Guidance literature:: Multi-step reaction with 4 steps

1.1: 100 percent / hydrogen; Et₃N / Pd-C / ethyl acetate / 0.75 h / 20 °C

2.1: NaH / toluene / 15 h / 110 °C

2.2: 78 percent / aq. HCl / dioxane / 15 h / 70 °C

3.1: 83 percent / NaOH / ethanol; H₂O / 15 h / 20 °C

4.1: 60 percent / potassium tert-butoxide / dimethylsulfoxide / 5 h / 100 °C

With sodium hydroxide; potassium tert-butylate; hydrogen; sodium hydride; triethylamine; palladium on activated charcoal; In ethanol; water; dimethyl sulfoxide; ethyl acetate; toluene;
DOI:10.1021/jo701435p

Reference yield:

: 2-[(2,4,5-trimethoxyphenyl)amino]-2-butenedioic acid dimethyl ester

: 957785-28-3
3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone

Guidance literature:: Multi-step reaction with 6 steps

1.1: 86 percent / diphenyl ether / 2 h / Heating

2.1: 88 percent / POCl₃ / benzene / 24 h / 20 °C

3.1: 100 percent / hydrogen; Et₃N / Pd-C / ethyl acetate / 0.75 h / 20 °C

4.1: NaH / toluene / 15 h / 110 °C

4.2: 78 percent / aq. HCl / dioxane / 15 h / 70 °C

5.1: 83 percent / NaOH / ethanol; H₂O / 15 h / 20 °C

6.1: 60 percent / potassium tert-butoxide / dimethylsulfoxide / 5 h / 100 °C

With sodium hydroxide; potassium tert-butylate; hydrogen; sodium hydride; triethylamine; trichlorophosphate; palladium on activated charcoal; In diphenylether; ethanol; water; dimethyl sulfoxide; ethyl acetate; toluene; benzene;
DOI:10.1021/jo701435p