957785-27-2

Upstream product

• 957785-26-1 1-[(5,6,8-trimethoxy)-2-quinolinyl]-ethanone 
• 6527-13-5 3,4-dimethoxy-(phenylmethoxy)benzaldehyde 
• 2103-57-3 2,3,4-trimethoxybenzaldehyde 
• 26510-91-8 2,4,5-trimethoxyaniline 
• 19283-70-6 3,4-dimethoxysalicylaldehyde 
• 957785-10-3 5,6,8-trimethoxyquinoline-2-carboxylic acid methyl ester 
• 957785-13-6 4-chloro-5,6,8-trimethoxyquinoline-2-carboxylic acid methyl ester 
• 957785-12-5 5,6,8-trimethoxy-(1H)-quinolin-4-one-2-carboxylic acid methyl ester 

Downstream Products

• 957785-28-3 3-methyl-4-[(3,4-dimethoxy-2-phenylmethoxy)phenyl]-6-[(5,6,8-trimethoxy)-2-quinolinyl]-(1H)-2-pyridinone 
• 957785-29-4 C₃₃H₃₁IN₂O₇ 
• 957785-30-7 2-[5,6,8-trimethoxy-2-quinolinyl]-4-[3,4-dimethoxy-2-(phenylmethoxy)phenyl]-6-benzyloxy-5-methyl-3-iodopyridine 
• 957785-31-8 C₄₁H₃₈N₂O₉ 
• 957785-32-9 2-[5,6,8-trimethoxy-2-quinolinyl]-4-[3,4-dimethoxy-2-(phenylmethoxy)phenyl]-6-benzyloxy-5-methyl-3-(N-phenylmethoxycarbonyl)pyridinamine 
• 957785-33-0 2-[3-(N-phenylmethoxycarbonyl)amino-4-(2-phenylmethoxy-3,4-dimethoxy)phenyl-5-methyl-6-phenylmethoxy]-2-pyridinyl-6-methoxyquinoline-5,8-dione 
• 957785-34-1 2-[3-(N-phenylmethoxycarbonyl)amino-4-(2-phenylmethoxy-3,4-dimethoxy)phenyl-5-methyl-6-phenylmethoxy]-2-pyridinyl-7-amino-6-methoxyquinoline-5,8-dione 

Relevant academic research and scientific papers

Total synthesis of streptonigrone

(Chemical Equation Presented) A total synthesis of streptonigrone, 1, is described, which incorporates a one-step synthesis of substituted pyridones devised in our laboratory. Other aspects of the synthesis that differentiate the present approach from previous ones are the use of a Conrad-Limpach reaction, rather than the customary Friedlaender methodology, to assemble the quinoline segment of 1, and the implementation of an anionic sequence for the functionalization of a key pyridone intermediate.