trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone

Base Information

• Chemical Name: trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone
• CAS No.: 1190364-33-0
• Molecular Formula: C₁₉H₁₈O₄
• Molecular Weight: 310.35
• Mol file: 1190364-33-0.mol

Synonyms:trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone

Chemical Property of trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone

There total 2 articles about trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

bromobenzene (108-86-1,52753-63-6) + Dimethyl itakonate (617-52-7) + benzaldehyde (100-52-7) → trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone (1190364-33-0)

Guidance literature:

With cobalt(II) bromide; zinc; In dodecane; ethylene dibromide; acetonitrile; trifluoroacetic acid; at 60 ℃; Inert atmosphere;

DOI:10.1016/j.tetlet.2009.07.038

Reference yield: 45.0%

iodobenzene (591-50-4) + Dimethyl itakonate (617-52-7) + benzaldehyde (100-52-7) → trans-3-(p-benzyl-4-phenyl-3-methoxycarbonyl)-γ-butyrolactone (1190364-33-0)

Guidance literature:

With ethylene dibromide; trifluoroacetic acid; cobalt(II) bromide; zinc; In acetonitrile; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/ejoc.201000698

upstream raw materials:

bromobenzene

Dimethyl itakonate

benzaldehyde

iodobenzene