Technology Process of (E)-N,N-dibenzyl-4-oxo-4-phenylbut-2-enamide
There total 1 articles about (E)-N,N-dibenzyl-4-oxo-4-phenylbut-2-enamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Benzoylacrylic acid;
With
4-methyl-morpholine; isobutyl chloroformate;
In
tetrahydrofuran;
at -30 - 0 ℃;
for 1h;
Inert atmosphere;
Schlenk technique;
dibenzylamine;
In
tetrahydrofuran;
at -20 - 0 ℃;
for 1h;
Inert atmosphere;
Schlenk technique;
DOI:10.1002/adsc.201700541
- Guidance literature:
-
With
C34H36F6MnN6O6S2; dihydrogen peroxide; acetic acid;
In
dichloromethane; acetonitrile;
at -30 ℃;
for 0.583333h;
enantioselective reaction;
Inert atmosphere;
Schlenk technique;
DOI:10.1002/adsc.201700541
- Guidance literature:
-
(E)-N,N-dibenzyl-4-oxo-4-phenylbut-2-enamide;
With
C28H26F6N4S;
In
toluene;
at 0 ℃;
for 0.5h;
2-methylpropan-2-thiol;
In
toluene;
at 0 ℃;
for 96h;
optical yield given as %ee;
DOI:10.1002/adsc.201100227
