2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester

Base Information

• Chemical Name: 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester
• CAS No.: 102618-08-6
• Molecular Formula: C₁₄H₁₃Cl₂FN₂O₄
• Molecular Weight: 363.173
• Mol file: 102618-08-6.mol

Synonyms:2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester

Chemical Property of 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester

There total 2 articles about 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1-Methyl-1-formylhydrazid (758-17-8) + 2,4-dichloro-alpha(elhoxymethlene)-5-fluoro-beta-oxo-benzene propanoic acid ethyl ester (86483-52-5) → 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester (102618-08-6)

Guidance literature:

In ethanol; for 1h; Ambient temperature;

Reference yield:

ethyl 3-dimethylamino-2-(2,4-dichloro-5-fluorobenzoyl)-acrylate + 1-Methyl-1-formylhydrazid (758-17-8) → 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester (102618-08-6)

Guidance literature:

In acetic acid;

Reference yield: 84.0%

2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester (102618-08-6) → ethyl 1-(N-formyl-N-methyl)amino-6-fluoro-7-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylate (88569-34-0)

Guidance literature:

With sodium hydride; In 1,4-dioxane; 1. 10 min., room temp. 2. 2.5 h, reflux;

upstream raw materials:

1-Methyl-1-formylhydrazid

2,4-dichloro-alpha(elhoxymethlene)-5-fluoro-beta-oxo-benzene propanoic acid ethyl ester

Downstream raw materials:

ethyl 1-(N-formyl-N-methyl)amino-6-fluoro-7-chloro-1,4-dihydro-4-oxoquinoline-3-carboxylate

6-fluoro-7-chloro-1-methylamino-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid

A 56559