86483-52-5

Usage

Uses

Used in Pharmaceutical Industry:
(Z)-2-(2,4-DICHLORO-5-FLUORO-BENZOYL)-3-ETHOXY-ACRYLIC ACID ETHYL ESTER is used as a key intermediate for the production of various pharmaceuticals. Its unique molecular structure contributes to the development of new drugs with potential therapeutic benefits.
Used in Agrochemical Industry:
In the agrochemical industry, (Z)-2-(2,4-DICHLORO-5-FLUORO-BENZOYL)-3-ETHOXY-ACRYLIC ACID ETHYL ESTER is used as a crucial component in the synthesis of different agrochemicals, such as pesticides and herbicides, due to its potential to enhance their effectiveness and target-specific action.
Used in Organic Chemistry:
(Z)-2-(2,4-DICHLORO-5-FLUORO-BENZOYL)-3-ETHOXY-ACRYLIC ACID ETHYL ESTER serves as an important building block in organic chemistry, facilitating the synthesis of complex organic molecules and contributing to the advancement of chemical research and development.
Used in Material Science and Technology Development:
This chemical compound may also have potential applications in the development of new materials and technologies, thanks to its unique chemical properties, which could lead to innovative solutions in various industries.

Upstream product

• 1435-48-9 1,3-dichloro-4-fluorobenzene 
• 86483-50-3 diethyl 2,4-dichloro-5-fluoro-benzoyl-malonate 
• 86393-34-2 2,4-dichloro-5-fluorobenzoyl chloride 
• 704-10-9 2,4-dichloro-5-fluoroacetophenone 
• 86483-51-4 ethyl 2,4-dichloro-5-fluoro-benzoyl-acetate 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 102618-08-6 2-(2,4-Dichlor-5-fluor-benzoyl)-3-(2-formyl-2-methylhydrazino)acrylsaeure-ethylester 
• 118539-49-4 (Z)-2-(2,4-Dichloro-5-fluoro-benzoyl)-3-(2,2-dimethyl-cyclopropylamino)-acrylic acid ethyl ester 
• 98105-70-5 (Z)-3-(Benzo[1,3]dioxol-5-ylamino)-2-(2,4-dichloro-5-fluoro-benzoyl)-acrylic acid ethyl ester 
• 109308-87-4 3-(Dimethylhydrazino)-2-(2,4-dichlor-5-fluorbenzoyl)-acrylsaeure-ethylester 
• 116163-40-7 3-(2,4-dichloro-5-fluorophenyl)-3-oxo-2-(((1,1-dimethylethyl)amino)methylene)propanoic acid etyhyl ester 
• 109308-96-5 5-(2,4-Dichlor-5-fluorphenyl)-1-methyl-4-pyrazolcarbonsaeure-ethylester 
• 109308-76-1 3-(2,4-Dichlor-5-fluorphenyl)-1-methyl-4-pyrazolcarbonsaeure-ethylester 
• 85721-33-1 ciprofloxacin 
• 86393-33-1 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinoline carboxylic acid 
• 93107-08-5 ciprofloxacin hydrochloride 
• 93106-60-6 enrofloxacin 
• 98105-68-1 (Z)-2-(2,4-Dichloro-5-fluoro-benzoyl)-3-(4-methoxy-phenylamino)-acrylic acid ethyl ester 
• 98105-69-2 (Z)-2-(2,4-Dichloro-5-fluoro-benzoyl)-3-p-tolylamino-acrylic acid ethyl ester 
• 98105-67-0 (Z)-2-(2,4-Dichloro-5-fluoro-benzoyl)-3-(4-hydroxy-phenylamino)-acrylic acid ethyl ester 

Relevant academic research and scientific papers

ANTIVIRAL AND ANTIMICROBIAL COMPOUNDS

Disclosed are guanidine and biguanidine derivatives which have anti-viral and antibacterial activity. Also disclosed are pharmaceutical compositions containing such compounds as an active ingredient, and anti-viral and anti-bacterial methods utilizing such compounds. Methods of treating infections using the guanidine and biguanidine derivatives are also disclosed.

On the binding site of quinolone antibacterials. An attempt to probe the Shen model

Quinolone-nuclei acid base hybrids were synthesized in an effort to probe a mechanistic model and a proposed mode of antibacterial action where stacked pairs of quinolones interact with DNA through H-bonding.

Synthesis and antibacterial activity of 1-(substituted pyrrolyl)-7- (substituted amino)-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids

Seventeen quinolone compounds characterized by having a fluorine atom at the 6-position, a substituted amino at the 7-position, and a substituted pyrrolyl at the 1-position were synthesized for the first time. The in vitro antibacterial activities of thes

Cycloaracylation of Enamines, I. - Synthesis of 4-Quinolone-3-carboxylic Acids

Starting with o-halobenzoyl chlorides 4 and open-chain secondary enamines 5, a new synthesis of 4-quinolone-3-carboxylic acids 12 is described.The reaction of 7-haloquinolone-3-carboxylic acids 12a-k with aliphatic amines 14 produces highly active antibacterial 7-aminoquinolone-3-carboxylic acids 15.The main product of the 1-cyclopropyl series, "ciprofloxacin" (15a), is being developed as a broad-spectrum chemotherapeutic agent.

Synthesis and Structure-Activity Relationships of Novel Arylfluoroquinolone Antibacterial Agents

A series of novel arylfluoroquinolones has been prepared.These derivatives are characterized by having a fluorine atom at the 6-position, substituted amino groups at the 7-position, and substituted phenyl groups at the 1-position.Structure-activity relationship (SAR) studies indicate that the in vitro antibacterial potency is greatest when the 1-substituent is either p-fluorophenyl or p-hydroxyphenyl and the 7-substituent is either 1-piperazinyl, 4-methyl-1-piperazinyl, or 3-amino-1-pyrrolidinyl.The electronic and spatial properties of the 1-substituent, as well as the steric bulk, play important roles in the antimicrobial potency in this class of antibacterials.As a result of this study, compounds 45 and 41 were found to possess excellent in vitro potency and in vivo efficacy.