2,6-di-tert-butyl-4-methylphenyl benzoate

Base Information

• Chemical Name: 2,6-di-tert-butyl-4-methylphenyl benzoate
• CAS No.: 30392-17-7
• Molecular Formula: C₂₂H₂₈O₂
• Molecular Weight: 324.463
• Mol file: 30392-17-7.mol

Synonyms:2,6-di-tert-butyl-4-methylphenyl benzoate

Chemical Property of 2,6-di-tert-butyl-4-methylphenyl benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,6-di-tert-butyl-4-methylphenyl benzoate

There total 5 articles about 2,6-di-tert-butyl-4-methylphenyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 7.0%

2,6-di-tert-butyl-4-methyl-phenol (128-37-0) + Benzoylformic acid (611-73-4) → 2,6-di-tert-butyl-4-methylphenyl benzoate (30392-17-7)

Guidance literature:

With dipotassium peroxodisulfate; silver carbonate; In acetonitrile; at 100 ℃; for 24h; Schlenk technique; Inert atmosphere; Glovebox;

DOI:10.1016/j.tetlet.2017.11.005

Reference yield:

2,6-di-tert-butyl-4-methyl-phenol (128-37-0) → 2,6-di-tert-butyl-4-methylphenyl benzoate (30392-17-7)

Guidance literature:

With sodium-potassium alloy; diethyl ether; Erwaermen des erhaltenen Gemisches von Alkalisalzen mit Benzoylchlorid in Petrolaether;

DOI:10.1021/ja01218a045

Reference yield:

p-cresol (106-44-5) → 2,6-di-tert-butyl-4-methylphenyl benzoate (30392-17-7)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated sulfuric acid / <70

2: sodium-potassium-alloy; diethyl ether / Erwaermen des erhaltenen Gemisches von Alkalisalzen mit Benzoylchlorid in Petrolaether

With sodium-potassium alloy; diethyl ether; sulfuric acid;

DOI:10.1021/ja01218a045

upstream raw materials:

2,6-di-tert-butyl-4-methyl-phenol

p-cresol

Benzoylformic acid

acetophenone

Refernces

• 1、 Wu, Shang,Yu, Hongheng,Hu, Qinzheng,Yang, Quanlu,Xu, Shouwang,Liu, Tian. "Silver-catalyzed decarboxylative cross-coupling of α-keto acids with alkenes giving approach to chalcones". supporting information. p. 4763 - 4765. Retrieved 2017/12/01.