Reboxetine Methanesulfonate

Base Information

Chemical Name:Reboxetine Methanesulfonate
CAS No.:98769-82-5
Molecular Formula:CH₄O₃S*C₁₉H₂₃NO₃
Molecular Weight:409.503
Hs Code.:

Synonyms:Reboxetine methanesulfonate

Suppliers and Price of Reboxetine Methanesulfonate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 11 raw suppliers

Chemical Property of Reboxetine Methanesulfonate

Chemical Property:

Vapor Pressure:4.54E-08mmHg at 25°C
Melting Point:145-146°
Boiling Point:443.7 °C at 760 mmHg
Flash Point:188.2 °C
PSA：102.47000
LogP:4.10740

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Reboxetine Methanesulfonate

There total 19 articles about Reboxetine Methanesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 2-chloro-N-[3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropyl]acetamide

: 93851-87-7,98769-82-5,98769-84-7,98819-77-3,105017-39-8,141425-90-3
Reboxetine mesylate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium tert-butylate / isopropyl alcohol; tert-butyl alcohol

2: methanesulfonic acid / acetone

With methanesulfonic acid; potassium tert-butylate; In isopropyl alcohol; acetone; tert-butyl alcohol;
DOI:10.1039/c1gc15921f

Reference yield:

: 93853-04-4,98769-75-6
(2RS,3RS)-1-amino-3-(2-ethoxyphenoxy)-2-hydroxy-3-phenylpropane methanesulfonate

: 93851-87-7,98769-82-5,98769-84-7,98819-77-3,105017-39-8,141425-90-3
Reboxetine mesylate

Guidance literature:: Multi-step reaction with 3 steps

1: carbonic acid dimethyl ester / ethanol

2: potassium tert-butylate / isopropyl alcohol; tert-butyl alcohol

3: methanesulfonic acid / acetone

With methanesulfonic acid; potassium tert-butylate; carbonic acid dimethyl ester; In ethanol; isopropyl alcohol; acetone; tert-butyl alcohol;
DOI:10.1039/c1gc15921f

Reference yield:

: 98769-72-3,98819-72-8
(2RS,3RS)-3-(2-ethoxyphenoxy)-3-phenylpropene-1,2-epoxide

: 93851-87-7,98769-82-5,98769-84-7,98819-77-3,105017-39-8,141425-90-3
Reboxetine mesylate

Guidance literature:: Multi-step reaction with 4 steps

1: methanol; ammonia / isopropyl alcohol

2: carbonic acid dimethyl ester / ethanol

3: potassium tert-butylate / isopropyl alcohol; tert-butyl alcohol

4: methanesulfonic acid / acetone

With methanol; methanesulfonic acid; potassium tert-butylate; ammonia; carbonic acid dimethyl ester; In ethanol; isopropyl alcohol; acetone; tert-butyl alcohol;
DOI:10.1039/c1gc15921f