1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate

Base Information

• Chemical Name: 1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate
• CAS No.: 223589-01-3
• Molecular Formula: C₂H₂O₄*C₁₉H₂₃ClN₄
• Molecular Weight: 432.907
• Mol file: 223589-01-3.mol

Synonyms:1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate

Chemical Property of 1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate

There total 2 articles about 1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

1-[(4-chlorophenyl)methyl]piperazine (23145-88-2) + oxalic acid (144-62-7,97993-78-7) + 2-chloro-5,6,7,8-tetrahydroquinazoline (81532-76-5) → 1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate (223589-01-3)

Guidance literature:

1-[(4-chlorophenyl)methyl]piperazine; 2-chloro-5,6,7,8-tetrahydroquinazoline; at 150 ℃; for 0.5h;

oxalic acid; In isopropyl alcohol;

Reference yield:

1-[(4-chlorophenyl)methyl]piperazine (23145-88-2) → 1-(5,6,7,8-tetrahydroquinazolin-2-yl)-4-(1-[4-chlorophenyl]methyl)-piperazine oxalate (223589-01-3)

Guidance literature:

With oxalic acid; In isopropyl alcohol;

upstream raw materials:

1-[(4-chlorophenyl)methyl]piperazine

oxalic acid

2-chloro-5,6,7,8-tetrahydroquinazoline