2-Bromocycloheptan-1-ol

Base Information

• Chemical Name: 2-Bromocycloheptan-1-ol
• CAS No.: 74305-05-8
• Molecular Formula: C₇H₁₃BrO
• Molecular Weight: 193.084
• DSSTox Substance ID: DTXSID601315208
• Mol file: 74305-05-8.mol

Synonyms:2-bromocycloheptan-1-ol;74305-05-8;2-bromocycloheptanol;DTXSID601315208;AKOS017531074;EN300-1136745

Chemical Property of 2-Bromocycloheptan-1-ol

Chemical Property:

• XLogP3: 2.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 192.01498
• Heavy Atom Count: 9
• Complexity: 85

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CCC(C(CC1)Br)O

Technology Process of 2-Bromocycloheptan-1-ol

There total 1 articles about 2-Bromocycloheptan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

Cycloheptene (628-92-2,45509-99-7) → 1,2-dibromocycloheptane (29974-68-3) + 2-bromocycloheptanone (1056246-49-1) + 2-Bromo-cycloheptanol (74305-05-8)

Guidance literature:

With sodium bromate; sulfuric acid; sodium bromide; In 1,4-dioxane; water; at 20 ℃; for 9h;

DOI:10.1016/j.tetlet.2009.03.047

Reference yield: 83.0%

trans-1-Brom-2-hydroxycycloheptan (68522-08-7,74305-05-8,84402-54-0) + (2,2-diphenylhydrazono)acetic acid (728-15-4) → trans-2-bromocycloheptyl (diphenylhydrazono)acetate

Guidance literature:

With dmap; dicyclohexyl-carbodiimide; In dichloromethane; for 12h;

DOI:10.1021/jo0013655

Reference yield:

2-Bromo-cycloheptanol (74305-05-8) → cycloheptanol (502-41-0)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOH

2: propan-2-ol / Irradiation

With sodium hydroxide; In isopropyl alcohol;

upstream raw materials:

Cycloheptene

Downstream raw materials:

8-oxabicyclo[5.1.0]octane

cycloheptanol

cycloheptanone