2-nitro-3-N-benzylaminobenzothiophene

Base Information

• Chemical Name: 2-nitro-3-N-benzylaminobenzothiophene
• CAS No.: 58763-85-2
• Molecular Formula: C₁₅H₁₂N₂O₂S
• Molecular Weight: 284.338
• Mol file: 58763-85-2.mol

Synonyms:2-nitro-3-N-benzylaminobenzothiophene

Chemical Property of 2-nitro-3-N-benzylaminobenzothiophene

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-nitro-3-N-benzylaminobenzothiophene

There total 1 articles about 2-nitro-3-N-benzylaminobenzothiophene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-bromo-2-nitro-1-benzothiophene (17402-78-7) + benzylamine (100-46-9) → 2-nitro-3-N-benzylaminobenzothiophene (58763-85-2)

Guidance literature:

In N,N-dimethyl-formamide; at 60 ℃; for 0.25h;

Reference yield: 85.0%

2-nitro-3-N-benzylaminobenzothiophene (58763-85-2) + Ethyl oxalyl chloride (4755-77-5) → N-Benzyl-N-(2-nitro-benzo[b]thiophen-3-yl)-oxalamic acid ethyl ester (132715-23-2)

Guidance literature:

In 1,4-dioxane; for 12h; Ambient temperature;

Reference yield: 50.0%

2-oxo-3-(phenyl)propionic acid (156-06-9) + 2-nitro-3-N-benzylaminobenzothiophene (58763-85-2) → 1,3-dibenzyl<1>benzothieno<2,3-b>pyrazin-2(1H)-one

Guidance literature:

With hydrogen; palladium on activated charcoal; In acetic acid; for 15h; Ambient temperature;

upstream raw materials:

3-bromo-2-nitro-1-benzothiophene

benzylamine

Downstream raw materials:

2-phenyl-benzo[4,5]thieno[2,3-d]imidazol-3-ol

N-Benzyl-N-(2-nitro-benzo[b]thiophen-3-yl)-oxalamic acid ethyl ester

1-Benzyl-2-bromo-1H-benzo[4,5]thieno[2,3-d]imidazole

1-Benzyl-2-piperazin-1-yl-1H-benzo[4,5]thieno[2,3-d]imidazole