carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

Base Information

Chemical Name:carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester
CAS No.:1350551-87-9
Molecular Formula:C₂₆H₂₄FN₇O₆
Molecular Weight:549.518
Hs Code.:

carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

Synonyms:carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

Suppliers and Price of carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

There total 1 articles about carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7504-94-1
2-pyrimidinylhydrazine

: 1350551-86-8
carbonic acid {3-[1-(4-cyanophenylamino)-2-ethoxycarbonylimino-2-methylsulfanylethyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

: 1350551-87-9
carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

Guidance literature:: 2-pyrimidinylhydrazine; carbonic acid {3-[1-(4-cyanophenylamino)-2-ethoxycarbonylimino-2-methylsulfanylethyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester; In tetrahydrofuran; at 15 - 22 ℃; Inert atmosphere;

With 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; at 15 - 22 ℃; for 2.5h;

Reference yield:

: 1350551-87-9
carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

: 951805-75-7
carbonic acid 2-{3-[(4-cyanophenylamino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester methyl ester

Guidance literature:: carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester; With water; sodium hydroxide; In tetrahydrofuran; methanol; at 15 - 20 ℃; for 16h;

With acetic acid; In tetrahydrofuran; methanol; water; at 15 - 22 ℃; for 0.333333h;

Reference yield:

: 1350551-87-9
carbonic acid 2-{3-[(4-cyanophenylimino)-(5-oxo-1-pyrimidin-2-yl-4,5-dihydro-1H-[1,2,4]-triazol-3-yl)methyl]-2-fluoro-5-methoxyphenoxy}ethyl ester ethyl ester

: 1350551-52-8
3-methoxy-2,2-dimethylpropionic acid 5-[(R)-[3-(2-acetoxyethoxy)-2-fluoro-5-methoxyphenyl]-(4-{amino[2-methylallyloxycarbonylimino]methyl}phenylamino)methyl]-2-pyrimidin-2-yl-2H-[1,2,4]triazol-3-yloxymethyl ester methanesulfonate

Guidance literature:: Multi-step reaction with 8 steps

1.1: sodium hydroxide; water / tetrahydrofuran; methanol / 16 h / 15 - 20 °C

1.2: 0.33 h / 15 - 22 °C

2.1: acetyl chloride; methanol / 18.5 h / 5 - 10 °C

2.2: 18 h / 10 - 20 °C

2.3: 18 h / 20 °C

3.1: triethylamine / methanol / 0.25 h / 60 °C

3.2: 23 h / 0 - 20 °C

4.1: hydrogenchloride / ethanol; water; methanol / 20 °C

5.1: potassium carbonate / dimethyl sulfoxide / 96 h / 20 °C

6.1: triethylamine / dmap / N,N-dimethyl-formamide / 1.33 h / 20 °C

7.1: rubidium carbonate / N,N-dimethyl acetamide / 1.25 h / 85 °C / Inert atmosphere

8.1: ethyl acetate / 20 °C

With rubidium carbonate; hydrogenchloride; methanol; water; potassium carbonate; triethylamine; acetyl chloride; sodium hydroxide; dmap; In tetrahydrofuran; methanol; ethanol; N,N-dimethyl acetamide; water; dimethyl sulfoxide; ethyl acetate; N,N-dimethyl-formamide;