2(1H)-Pyrimidinone, hydrazone (9CI)

Base Information

• Chemical Name: 2(1H)-Pyrimidinone, hydrazone (9CI)
• CAS No.: 7504-94-1
• Molecular Formula: C4H6N4
• Molecular Weight: 110.118
• Hs Code.: 29339900
• Mol file: 7504-94-1.mol

Synonyms:2(1H)-Pyrimidinone,hydrazone (9CI);Pyrimidine, 2-hydrazino- (7CI,8CI);2-Hydrazinopyrimidine;2-Pyrimidinylhydrazine;NSC 404821;

Chemical Property of 2(1H)-Pyrimidinone, hydrazone (9CI)

Chemical Property:

• Vapor Pressure: 0.00196mmHg at 25°C
• Melting Point: 86-88 °C(Solv: benzene (71-43-2))
• Refractive Index: 1.673
• Boiling Point: 291.3 °C at 760 mmHg
• PKA: 6.17±0.20(Predicted)
• Flash Point: 130 °C
• PSA: 67.06000
• Density: 1.334 g/cm³
• LogP: -0.11560
• Storage Temp.: Keep in dark place,Inert atmosphere,Store in freezer, under -20°C

Purity/Quality:

97% ^*data from raw suppliers

2-Hydrazinopyrimidine ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2(1H)-Pyrimidinone, hydrazone (9CI)

There total 4 articles about 2(1H)-Pyrimidinone, hydrazone (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.8%

2-chloropyrimidine (1722-12-9,1195939-87-7) → 2-pyrimidinylhydrazine (7504-94-1)

Guidance literature:

With potassium carbonate; hydrazine hydrate; at 100 ℃; for 0.5h;

Reference yield: 83.0%

2-chloropyrimidine (1722-12-9,1195939-87-7) + hydrazine (302-01-2,78206-91-4,119775-10-9,75013-58-0) → 2-pyrimidinylhydrazine (7504-94-1)

Guidance literature:

With pyridine; at 20 ℃; for 3h;

Reference yield:

2-methoxypyrimidine (931-63-5) → 2-pyrimidinylhydrazine (7504-94-1)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

2-chloropyrimidine

2-methoxypyrimidine

hydrazine

Downstream raw materials:

3-Methyl-s-triazolo<4,3-a>pyrimidin

C₁₉H₁₇N₆⁽¹⁺⁾*BrH*Br^(1-)

2-(5-O-benzoyl-β-D-ribofuranosyl)-1,2,4-triazolo<1,5-a>pyrimidine

3-[4-(3-chloro-phenyl)-piperazin-1-yl]-1-(5-phenyl-1-pyrimidin-2-yl-1H-pyrazol-4-yl)-propan-1-one