H₂apahC₆H₄-4-OCH₃

Base Information

• Chemical Name: H₂apahC₆H₄-4-OCH₃
• CAS No.: 142068-24-4
• Molecular Formula: C₁₆H₁₆N₂O₂
• Molecular Weight: 268.315
• Mol file: 142068-24-4.mol

Synonyms:H₂apahC₆H₄-4-OCH₃

Chemical Property of H₂apahC₆H₄-4-OCH₃

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of H₂apahC₆H₄-4-OCH₃

There total 6 articles about H₂apahC₆H₄-4-OCH₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

4-methoxybenzoic acid hydrazide (3290-99-1) + phenylacetylene (536-74-3) → (E)-4-methoxy-N'-(1-phenylethylidene)benzohydrazide (142068-24-4)

Guidance literature:

With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); In chlorobenzene; at 60 ℃; for 2h;

DOI:10.1021/acs.orglett.8b02019

Reference yield: 69.0%

4-methoxybenzoic acid hydrazide (3290-99-1) + acetophenone (98-86-2) → H2apahC6H4-4-OCH3 (142068-24-4)

Guidance literature:

With acetic acid; In methanol; for 24h; Heating;

Reference yield: 67.0%

4-methoxybenzoic acid hydrazide (3290-99-1) + acetophenone (98-86-2) → (E)-4-methoxy-N'-(1-phenylethylidene)benzohydrazide (142068-24-4)

Guidance literature:

In methanol; at 20 ℃;

DOI:10.1021/acs.orglett.0c02756

upstream raw materials:

4-methoxybenzoic acid hydrazide

phenylacetylene

acetophenone

methyl 4-methoxybenzoate

Downstream raw materials:

4-methoxy-N'-(1-phenylethyl)benzohydrazide

(R)-1-phenyl-1-(2-p-methoxybenzoylhydrazino)ethane

(S)-1-phenyl-1-(2-p-methoxybenzoylhydrazino)ethane