C₁₉H₁₅FO

Base Information

• Chemical Name: C₁₉H₁₅FO
• CAS No.: 1100805-66-0
• Molecular Formula: C₁₉H₁₅FO
• Molecular Weight: 278.326
• Mol file: 1100805-66-0.mol

Synonyms:C₁₉H₁₅FO

Chemical Property of C₁₉H₁₅FO

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₉H₁₅FO

There total 4 articles about C₁₉H₁₅FO which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

fluorobenzene (462-06-6) + 2-Phenylbenzaldehyde (1203-68-5) → C19H15FO (1100805-66-0)

Guidance literature:

fluorobenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -50 ℃; for 1h; Inert atmosphere;

2-Phenylbenzaldehyde; In tetrahydrofuran; hexane; at -50 - 20 ℃; for 3h; Inert atmosphere;

DOI:10.1002/ejoc.201901278

Reference yield:

2-biphenylmethanol (2928-43-0) → C19H15FO (1100805-66-0)

Guidance literature:

Multi-step reaction with 2 steps

1.1: manganese(IV) oxide / dichloromethane / Reflux

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -50 °C / Inert atmosphere

2.2: 3 h / -50 - 20 °C / Inert atmosphere

With manganese(IV) oxide; n-butyllithium; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1002/ejoc.201901278

Reference yield:

2-Biphenylcarboxylic acid (947-84-2) → C19H15FO (1100805-66-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 0 - 20 °C / Inert atmosphere

2.1: manganese(IV) oxide / dichloromethane / Reflux

3.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -50 °C / Inert atmosphere

3.2: 3 h / -50 - 20 °C / Inert atmosphere

With manganese(IV) oxide; lithium aluminium tetrahydride; n-butyllithium; In tetrahydrofuran; hexane; dichloromethane;

DOI:10.1002/ejoc.201901278

upstream raw materials:

2-Phenylbenzaldehyde

4-flourophenylmagnesium bromide

fluorobenzene

2-Biphenylcarboxylic acid

Downstream raw materials:

9-(4-fluorophenyl)fluorene

6-(4′-fluorophenyl)phenanthridine