{3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol

Base Information

• Chemical Name: {3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol
• CAS No.: 1422953-11-4
• Molecular Formula: C₂₆H₄₀O₅
• Molecular Weight: 432.601
• Mol file: 1422953-11-4.mol

Synonyms:{3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol

Chemical Property of {3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of {3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol

There total 1 articles about {3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

farnesyl bromide (24163-93-7,24163-94-8,56881-57-3,6874-67-5,28290-41-7) + [3,5-bis(methoxymethoxy)phenyl]methanol (76280-60-9) → {3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol (1422953-11-4)

Guidance literature:

[3,5-bis(methoxymethoxy)phenyl]methanol; With copper(I) bromide dimethylsulfide complex; N,N,N,N,-tetramethylethylenediamine; tert.-butyl lithium; In tetrahydrofuran; pentane; at -20 ℃; for 2h; Inert atmosphere;

farnesyl bromide; In tetrahydrofuran; pentane; at -20 ℃; for 2h; Inert atmosphere;

DOI:10.1055/s-0032-1317544

Reference yield: 88.0%

{3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol (1422953-11-4) → 3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzaldehyde (1422953-12-5)

Guidance literature:

With pyridinium chlorochromate; In dichloromethane; at 0 - 25 ℃; for 3h; Molecular sieve; Inert atmosphere;

DOI:10.1055/s-0032-1317544

Reference yield:

{3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]phenyl}methanol (1422953-11-4) → 3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzoic acid (1422953-13-6)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium chlorochromate / dichloromethane / 3 h / 0 - 25 °C / Molecular sieve; Inert atmosphere

2: 2-methyl-but-2-ene; sodium dihydrogenphosphate; sodium chlorite / tert-butyl alcohol; water / 8 h / 25 °C

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; pyridinium chlorochromate; In dichloromethane; water; tert-butyl alcohol;

DOI:10.1055/s-0032-1317544

upstream raw materials:

farnesyl bromide

[3,5-bis(methoxymethoxy)phenyl]methanol

Downstream raw materials:

3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzaldehyde

3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzoic acid

N,N-diethyl-3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzamide

N,N-diethyl-2-formyl-3,5-bis(methoxymethoxy)-4-[(2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-yl]benzamide