N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride

Base Information

• Chemical Name: N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride
• CAS No.: 372094-59-2
• Molecular Formula: C₁₉H₁₄ClN₃O₃*ClH
• Molecular Weight: 404.252

Synonyms:N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride

Chemical Property of N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride

Chemical Property:

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Technology Process of N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride

There total 1 articles about N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

N-[4-[4-(tert-butoxycarbonylamino)phenyl]phenyl]-(2-chloro-5-nitrophenyl)carboxamide (372094-58-1) → N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride (372094-59-2)

Guidance literature:

In 1,4-dioxane; hydrogenchloride;

Reference yield: 88.0%

N-[4-(4-aminophenyl)phenyl-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride + N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride (372094-59-2) + benzoyl chloride (98-88-4) → N-[4-(4-Benzoylaminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide (372094-92-3)

Guidance literature:

With 2,4-dichlorophenoxyacetic acid dimethylamine; triethylamine;

Reference yield: 86.0%

N-[4-(4-aminophenyl)phenyl-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride + N-[4-(4-aminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide mono-hydrochloride (372094-59-2) + acetyl chloride (75-36-5) → N-[4-(4-acetylaminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide (372094-90-1)

Guidance literature:

With 2,4-dichlorophenoxyacetic acid dimethylamine; triethylamine;

upstream raw materials:

N-[4-[4-(tert-butoxycarbonylamino)phenyl]phenyl]-(2-chloro-5-nitrophenyl)carboxamide

Downstream raw materials:

N-[4-(4-acetylaminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide

N-[4-[4-(Methanesulfonylamino)phenyl]phenyl]-(2-chloro-5-nitrophenyl)carboxamide

N-[4-(4-Ethanesulfonylaminophenyl)phenyl]-(2-chloro-5-nitrophenyl)carboxamide

N-[4-[4-(4-Toluenesulfonylamino)phenyl]phenyl]-(2-chloro-5-nitrophenyl)carboxamide

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