3-chloro-N-formylbenzamide

Base Information

• Chemical Name: 3-chloro-N-formylbenzamide
• CAS No.: 1426954-54-2
• Molecular Formula: C₈H₆ClNO₂
• Molecular Weight: 183.594
• Mol file: 1426954-54-2.mol

Synonyms:3-chloro-N-formylbenzamide

Chemical Property of 3-chloro-N-formylbenzamide

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-chloro-N-formylbenzamide

There total 2 articles about 3-chloro-N-formylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

3-chlorobenzamide (618-48-4) + carbon dioxide (124-38-9,18923-20-1) → 3-chloro-N-formylbenzamide (1426954-54-2)

Guidance literature:

With phenylsilane; C₃₉H₄₇N₂; In acetonitrile; at 20 ℃; for 24h; under 760.051 Torr;

DOI:10.1021/acscatal.8b04023

Reference yield: 46.0%

3-chlorobenzamide (618-48-4) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 3-chloro-N-formylbenzamide (1426954-54-2)

Guidance literature:

With N-Bromosuccinimide; water; at 80 ℃;

DOI:10.1039/c3ob27351b

upstream raw materials:

3-chlorobenzamide

N,N-dimethyl-formamide

carbon dioxide

Refernces

• 1、 Hota, Pradip Kumar,Sau, Samaresh Chandra,Mandal, Swadhin K.. "Metal-Free Catalytic Formylation of Amides Using CO2 under Ambient Conditions". . p. 11999 - 12003. Retrieved 2019/01/03.