5-Acetamidomethyl-4-Amino-2-Methyl pyrimidine

Base Information

• Chemical Name: 5-Acetamidomethyl-4-Amino-2-Methyl pyrimidine
• CAS No.: 23676-63-3
• Molecular Formula: C8H12N4O
• Molecular Weight: 180.209
• Hs Code.: 2933599090
• Mol file: 23676-63-3.mol

Synonyms:4-Amino-2-methyl-5-acetaminomethyl-pyrimdin;4-Amino-2-methyl-5-acetaminomethyl-pyrimidin;5-Acetamidomethyl-4-Amino-2-Methyl pyrimidine;N-[(4-Amino-2-methyl-5-pyrimidinyl)methyl]acetamide;2-Methyl-4-amino-5-acetamidomethyl-pyrimidin;N-(2-methyl-4-amino-5-pyrimidyl)methyl-acetamide;N-((4-Amino-2-methylpyrimidin-5-yl)methyl)acetamide;5-(Acetylaminomethyl)-4-amino-2-methylpyrimidine;

Chemical Property of 5-Acetamidomethyl-4-Amino-2-Methyl pyrimidine

Chemical Property:

• PSA: 80.90000
• LogP: 0.97540
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature

Purity/Quality:

99% ^*data from raw suppliers

N-((4-Amino-2-methylpyrimidin-5-yl)methyl)acetamide 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 5-Acetamidomethyl-4-Amino-2-Methyl pyrimidine

There total 10 articles about 5-Acetamidomethyl-4-Amino-2-Methyl pyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,7-dimethyl-3,4-dihydro-pyrimido[4,5-d]pyrimidine (36755-43-8) + acetic acid (64-19-7,77671-22-8) → N-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-acetamide (23676-63-3)

Guidance literature:

With ethanol; at 100 ℃;

Reference yield:

N-acetyl-2-cyanoethylamine (1119-50-2) → N-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-acetamide (23676-63-3)

Guidance literature:

With sodium methylate; formic acid ethyl ester; anschliessend mit Diaethylsulfat und Acetamidin;

Reference yield:

2-ethoxymethyl-3-amino-acrylonitrile (98484-37-8) + acetamidine (143-37-3) → N-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-acetamide (23676-63-3)

Guidance literature:

DOI:10.1246/bcsj.32.188

upstream raw materials:

2,7-dimethyl-3,4-dihydro-pyrimido[4,5-d]pyrimidine

1-methyl-4-nitrosobenzene

ethanol

acetic acid

Downstream raw materials:

5-(aminomethyl)-2-methylpyrimidin-4-amine

3-(4-amino-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-3H-thiazole-2-thione