8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

Base Information

Chemical Name:8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester
CAS No.:96865-89-3
Molecular Formula:C₂₃H₂₅N₅O₇
Molecular Weight:483.481
Hs Code.:

Synonyms:8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

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Chemical Property of 8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

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Technology Process of 8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

There total 6 articles about 8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 6066-82-6
1-hydroxy-pyrrolidine-2,5-dione

: 96865-83-7
XCC

: 96865-89-3
8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

: 96865-88-2
N-<<<<4-(1,3-dipropyl-8-xanthinyl)phenyl>oxy>methyl>carbonyl>-N,N'-dicyclourea

Guidance literature:: With dicyclohexyl-carbodiimide; In N,N-dimethyl-formamide; for 24h; Ambient temperature;
DOI:10.1021/jm00147a038

Reference yield: 48.0%

: 96865-83-7
XCC

: 538-75-0
dicyclohexyl-carbodiimide

: 96865-89-3
8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

: 96865-88-2
N-<<<<4-(1,3-dipropyl-8-xanthinyl)phenyl>oxy>methyl>carbonyl>-N,N'-dicyclourea

Guidance literature:: With 1-hydroxy-pyrrolidine-2,5-dione; In N,N-dimethyl-formamide; for 24h; Ambient temperature;
DOI:10.1021/jm00147a038

Reference yield:

: 81250-34-2
1,3-dipropyl-5,6-diaminouracil

: 96865-89-3
8-<4-<(carboxymethyl)oxy>phenyl>-1,3-dipropylxanthine N-Hydroxysuccinimide ester

Guidance literature:: Multi-step reaction with 4 steps

1: 86 percent / acetic acid / methanol / 0.25 h / Heating

2: 71 percent / ferric chloride / 24 h / Heating

3: 0.1N aq. NaOH / dimethylformamide / 0.5 h

4: 48 percent / dicyclohexylcarbodiimide / dimethylformamide / 24 h / Ambient temperature

With sodium hydroxide; iron(III) chloride; acetic acid; dicyclohexyl-carbodiimide; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm00147a038