1,1-Dimethylguanidine hydrochloride

Base Information

• Chemical Name: 1,1-Dimethylguanidine hydrochloride
• CAS No.: 22583-29-5
• Deprecated CAS: 41248-11-7
• Molecular Formula: C3H9 N3 . Cl H
• Molecular Weight: 123.586
• Hs Code.: 2925290090
• DSSTox Substance ID: DTXSID30884895
• Mol file: 22583-29-5.mol

Synonyms:1,1-dimethylguanidine hydrochloride;22583-29-5;N,N-Dimethylguanidine hydrochloride;Guanidine, N,N-dimethyl-, monohydrochloride;1,1-dimethylguanidine;hydrochloride;1,1-dimethylguanidinehydrochloride;1.1-DIMETHYLGUANIDINE HYDROCHLORIDE;1,1-Dimethylguanidine HCl;SCHEMBL2950547;DTXSID30884895;XAA58329;1,1-dimethyl-guanidine hydrochloride;MFCD00152443;AKOS025141974;1.1-DIMETHYLGUANIDINEHYDROCHLORIDE;CS-10201;EN300-180089;A919962

Chemical Property of 1,1-Dimethylguanidine hydrochloride

Chemical Property:

• Vapor Pressure: 30.4mmHg at 25°C
• Boiling Point: 104.7°Cat760mmHg
• Flash Point: 17.1°C
• PSA: 53.11000
• Density: 1.05g/cm³
• LogP: 1.04350
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 123.0563250
• Heavy Atom Count: 7
• Complexity: 57.1

Purity/Quality:

97% ^*data from raw suppliers

1,1-dimethylguanidinehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 3
• Hazard Codes: 3

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C(=N)N.Cl

Technology Process of 1,1-Dimethylguanidine hydrochloride

There total 2 articles about 1,1-Dimethylguanidine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

CYANAMID (420-04-2) + N,N-dimethylammonium chloride (506-59-2) → N,N-dimethylguanidinium hydrochloride (22583-29-5)

Guidance literature:

In water; at 120 ℃; for 3.5h; pH=8 - 9;

DOI:10.1080/10426500490459669

Reference yield:

→ N,N-dimethylguanidinium hydrochloride (22583-29-5)

Guidance literature:

Reference yield: 91.0%

2-phenyl-5-ethoxyoxazole-4-carboxylic acid chloride (54644-14-3) + N,N-dimethylguanidinium hydrochloride (22583-29-5) → N'-(5-Ethoxy-2-phenyl-oxazole-4-carbonyl)-N,N-dimethyl-guanidine (88584-29-6)

Guidance literature:

With sodium hydroxide; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1055/s-1983-30535

upstream raw materials:

CYANAMID

N,N-dimethylammonium chloride

Downstream raw materials:

1-[1-Amino-1-dimethylamino-meth-(E)-ylidene]-3-(2,4,6-trimethyl-benzoyl)-thiourea

(4,6-diphenyl-furo[2,3-d]pyrimidin-2-yl)-dimethyl-amine

dimethyl-(2,2,4,4-tetraphenyl-2λ⁵,4λ⁵-[1,3,5,2,4]triazadiphosphinin-6-yl)-amine

1,6-dihydro-4,6,6-trimethyl-2-dimethylaminopyrimidine