1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

Base Information

Chemical Name:1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole
CAS No.:1172074-20-2
Molecular Formula:C₂₅H₂₆N₄O₂S
Molecular Weight:446.573
Hs Code.:

Synonyms:1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

Chemical Property:

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Technology Process of 1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

There total 4 articles about 1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 13.0%

: 189560-86-9
1-benzyl-2-(piperazin-1-ylmethyl)-1H-benzo[d]imidazole

: 98-09-9
benzenesulfonyl chloride

: 1172074-20-2
1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

Guidance literature:: With pyridine; at 20 ℃; for 15h;

Reference yield:

: 6646-70-4
(1-benzyl-1H-benzo[d]imidazol-2-yl)methanol

: 1172074-20-2
1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

Guidance literature:: Multi-step reaction with 4 steps

1: thionyl chloride / chloroform / 18 h / 20 °C

2: triethylamine / acetonitrile / 18 h / 20 °C

3: hydrogenchloride / methanol; water / 1 h / 20 °C

4: pyridine / 15 h / 20 °C

With pyridine; hydrogenchloride; thionyl chloride; triethylamine; In methanol; chloroform; water; acetonitrile;

Reference yield:

: 189560-87-0
4-((1-benzyl-1H-benzo[d]imidazol-2-yl)methyl)piperazine-1-carbaldehyde

: 1172074-20-2
1-benzyl-2-((4-(phenylsulfonyl)piperazin-1-yl)methyl)-1H-benzo[d]imidazole

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / methanol; water / 1 h / 20 °C

2: pyridine / 15 h / 20 °C

With pyridine; hydrogenchloride; In methanol; water;