combretastatin D₂ methyl ether

Base Information

Chemical Name:combretastatin D₂ methyl ether
CAS No.:134209-01-1
Molecular Formula:C₁₉H₁₈O₄
Molecular Weight:310.35
Hs Code.:

combretastatin D<sub>2</sub> methyl ether

Synonyms:combretastatin D₂ methyl ether

Suppliers and Price of combretastatin D₂ methyl ether

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of combretastatin D₂ methyl ether

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of combretastatin D₂ methyl ether

There total 1 articles about combretastatin D₂ methyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 100-00-5
4-chlorobenzonitrile

: 134209-01-1
combretastatin D₂ methyl ether

Guidance literature:: Multi-step reaction with 10 steps

2: 80 percent / pyridine, piperidine

3: 85 percent / H₂ / 10 percent Pd/C

4: H₂SO₄, NaNO₂ / 5 °C

5: KI

6: 96 percent / K₂CO₃ / acetone

7: 56 percent / (PPh₃)2PdCl₂, CuI, Et₃N

8: 95 percent / H₂ / Pd-CaCO₃

9: 98 percent / 10 percent aq. methanolic KOH

10: 20 percent / diethyl azodicarboxylate, PPh₃ / toluene; tetrahydrofuran / 8 h / 25 °C

With piperidine; pyridine; bis-triphenylphosphine-palladium(II) chloride; potassium hydroxide; copper(l) iodide; sulfuric acid; hydrogen; potassium carbonate; triethylamine; triphenylphosphine; potassium iodide; sodium nitrite; diethylazodicarboxylate; palladium on activated charcoal; Lindlar's catalyst; In tetrahydrofuran; acetone; toluene;
DOI:10.1016/S0040-4039(00)74692-2