2-(4-methylphenyl)-2-propen-1-ol

Base Information

• Chemical Name: 2-(4-methylphenyl)-2-propen-1-ol
• CAS No.: 66520-90-9
• Molecular Formula: C₁₀H₁₂O
• Molecular Weight: 148.205
• Mol file: 66520-90-9.mol

Synonyms:2-(4-methylphenyl)-2-propen-1-ol

Chemical Property of 2-(4-methylphenyl)-2-propen-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-methylphenyl)-2-propen-1-ol

There total 13 articles about 2-(4-methylphenyl)-2-propen-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

para-bromotoluene (106-38-7) + allyl alcohol (107-18-6) → 2-(4-methylphenyl)-2-propen-1-ol (66520-90-9)

Guidance literature:

With 1,3-bis-(diphenylphosphino)propane; triethylamine; 1-butyl-3-methylimidazolium Tetrafluoroborate; palladium diacetate; In dimethyl sulfoxide; at 115 ℃; for 36h;

DOI:10.1039/b608033b

Reference yield: 88.0%

para-bromotoluene (106-38-7) + propargyl alcohol (107-19-7) → 2-(4-methylphenyl)-2-propen-1-ol (66520-90-9)

Guidance literature:

para-bromotoluene; With magnesium; In diethyl ether; at 0 ℃; for 2h; Reflux;

With copper(l) iodide; In diethyl ether; at 20 ℃; for 0.5h;

propargyl alcohol; In diethyl ether; for 24h; Reflux;

DOI:10.1002/chem.201300189

Reference yield: 83.0%

1-methyl-4-isopropenylbenzene (1195-32-0) → 2-(4-methylphenyl)-2-propen-1-ol (66520-90-9)

Guidance literature:

With palladium(II) trifluoroacetate; water; p-benzoquinone; In dimethyl sulfoxide; at 20 ℃; for 90h; regioselective reaction; Sealed tube; Green chemistry;

DOI:10.1039/c9ob00209j

upstream raw materials:

formaldehyd

α-chloro-p-methylstyrene

p-methyl-α-methylstyrene oxide

1-(1-bromoethenyl)-4-methylbenzene

Downstream raw materials:

N-methyl-N-(2-p-tolylallyl)aniline

N-allyl-N-(2-(p-tolyl)allyl)aniline

N,N-dibenzyl-2-p-tolyl-2-propen-1-amine

N-benzyl-N,N-bis-(2-(p-tolyl)allyl)amine