3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate

Base Information

Chemical Name:3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate
CAS No.:151782-59-1
Molecular Formula:C₆₃H₆₅N₄O₁₅PSe
Molecular Weight:1228.16
Hs Code.:

Synonyms:3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate

Suppliers and Price of 3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate

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Technology Process of 3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate

There total 1 articles about 3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 40615-39-2
5'-O-(4-4'-dimethoxytrityl)thymidine

: 151782-59-1
3',5'-O,O-bis(dimethoxytrityl)-dithymidilyl-3',5'-Se-methyl phosphoroselenoate

Guidance literature:: Multi-step reaction with 2 steps

1.1: 1H-tetrazole / CH₂Cl₂ / 1 h

1.2: 77 percent / Se / CH₂Cl₂ / 12 h

2.1: DBU / acetonitrile / 0.25 h

2.2: 68 percent / acetonitrile / 2 h

With 1H-tetrazole; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; acetonitrile;
DOI:10.1016/S0968-0896(01)00025-6