Technology Process of C25H23F5N2O5
There total 9 articles about C25H23F5N2O5 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
Dess-Martin periodane;
In
dichloromethane;
at 0 ℃;
for 1.66667h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C
2: Dess-Martin periodane / dichloromethane / 1.67 h / 0 °C
With
benzotriazol-1-ol; Dess-Martin periodane; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
dichloromethane; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: 4-methyl-morpholine / tetrahydrofuran / 1 h / -10 °C
2: diethyl ether / 0.5 h / 0 °C
3: hydrogen bromide / tetrahydrofuran; water / 1 h / 0 °C
4: potassium fluoride / N,N-dimethyl-formamide / 1 h / 20 °C
5: sodium tetrahydroborate / ethanol / 0.5 h / 0 °C
6: palladium 10% on activated carbon; hydrogen / methanol / 4 h / 20 °C
7: benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 0 - 20 °C
8: Dess-Martin periodane / dichloromethane / 1.67 h / 0 °C
With
4-methyl-morpholine; potassium fluoride; sodium tetrahydroborate; palladium 10% on activated carbon; hydrogen bromide; hydrogen; benzotriazol-1-ol; Dess-Martin periodane; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; methanol; diethyl ether; ethanol; dichloromethane; water; N,N-dimethyl-formamide;
4: modified Finkel-stein reaction;