Methyl 5-bromo-2-chloroisonicotinate

Base Information

• Chemical Name: Methyl 5-bromo-2-chloroisonicotinate
• CAS No.: 886365-28-2
• Molecular Formula: C7H5BrClNO2
• Molecular Weight: 250.479
• Hs Code.: 2933399090
• Mol file: 886365-28-2.mol

Synonyms:METHYL 5-BROMO-2-CHLOROISONICOTINATE; 5-Bromo-2-chloro-4-pyridinecarboxylic acid methyl ester; 5-Bromo-2-chloro-4-(methoxycarbonyl)pyridine;

Chemical Property of Methyl 5-bromo-2-chloroisonicotinate

Chemical Property:

• Vapor Pressure: 0.00263mmHg at 25°C
• Refractive Index: 1.568
• Boiling Point: 286.5oC at 760 mmHg
• PKA: -3.54±0.10(Predicted)
• Flash Point: 127.1oC
• PSA: 39.19000
• Density: 1.684
• LogP: 2.28410
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

97% ^*data from raw suppliers

Methyl5-bromo-2-chloroisonicotinate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl 5-bromo-2-chloroisonicotinate

There total 1 articles about Methyl 5-bromo-2-chloroisonicotinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

methanol (67-56-1) + 5-bromo-2-chloropyridine-4-carboxylic acid (886365-31-7) → methyl 5-bromo-2-chloropyridine-4-carboxylate (886365-28-2)

Guidance literature:

With thionyl chloride; at 75 ℃; for 8h;

Reference yield: 55.0%

methyl 5-bromo-2-chloropyridine-4-carboxylate (886365-28-2) + 1-Ethynyl-3,5-dimethoxy-benzene (171290-52-1) → methyl 2-chloro-5-((3,5-dimethoxyphenyl)ethynyl)isonicotinate

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; copper(l) iodide; triethylamine; In 1,4-dioxane; at 60 ℃; for 6h; Inert atmosphere;

Reference yield: 41.0%

methyl 5-bromo-2-chloropyridine-4-carboxylate (886365-28-2) + phenylboronic acid (98-80-6) → methyl 2-chloro-5-phenylisonicotinate

Guidance literature:

With (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; caesium carbonate; In water; N,N-dimethyl-formamide; at 5 ℃; for 4h; Inert atmosphere; Cooling with ice;

upstream raw materials:

methanol

5-bromo-2-chloropyridine-4-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 886365-28-2 Methyl 5-bromo-2-chloroisonicotinate

Send

Send

Metric Ton KG G Pound L ML

Send

Send