N-(2-hydroxyphenyl)-2-furfurylamine

Base Information

• Chemical Name: N-(2-hydroxyphenyl)-2-furfurylamine
• CAS No.: 86818-41-9
• Molecular Formula: C₁₁H₁₁NO₂
• Molecular Weight: 189.214
• Mol file: 86818-41-9.mol

Synonyms:N-(2-hydroxyphenyl)-2-furfurylamine

Chemical Property of N-(2-hydroxyphenyl)-2-furfurylamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(2-hydroxyphenyl)-2-furfurylamine

There total 7 articles about N-(2-hydroxyphenyl)-2-furfurylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

furfural (98-01-1) + 2-amino-phenol (95-55-6) → N-(2-hydroxyphenyl)-2-furfurylamine (86818-41-9)

Guidance literature:

With sodium tris(acetoxy)borohydride; In tetrahydrofuran; at 20 ℃;

DOI:10.1016/j.tet.2005.12.059

Reference yield: 80.0%

N-(2-hydroxyphenyl)-2-furancarboxamide (75748-52-6) → N-(2-hydroxyphenyl)-2-furfurylamine (86818-41-9)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 1h; Heating;

DOI:10.1246/bcsj.56.1107

Reference yield:

2-furancarbonyl chloride (527-69-5) → N-(2-hydroxyphenyl)-2-furfurylamine (86818-41-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 25 percent / Et₃N / CH₂Cl₂ / 2 h / Ambient temperature

2: 80 percent / LiAlH₄ / tetrahydrofuran / 1 h / Heating

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;

DOI:10.1246/bcsj.56.1107

upstream raw materials:

N-(2-hydroxyphenyl)-2-furancarboxamide

2-furfurylideneamino-phenol

furfural

2-amino-phenol

Downstream raw materials:

N-furfuryl-N-(2-hydroxyphenyl)-1,5-cyclohexadienecarboxamide

N-furfuryl-N-(2-hydroxyphenyl)-1-cyclohexanecarboxamide

Cyclopent-1-enecarboxylic acid furan-2-ylmethyl-(2-hydroxy-phenyl)-amide