N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide

Base Information

Chemical Name:N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide
CAS No.:1338221-34-3
Molecular Formula:C₄₂H₃₃N₃O₅
Molecular Weight:659.741
Hs Code.:

Synonyms:N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide

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Chemical Property of N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide

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Technology Process of N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide

There total 3 articles about N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 87700-72-9
6-methoxy-1-naphthoyl chloride

: 40040-81-1
2-amino-3-benzyl-5-(4-methoxyphenyl)-pyrazine

: 1338221-34-3
N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide

Guidance literature:: With pyridine; dmap; at 50 ℃; for 18h; Inert atmosphere;

Reference yield:

: 36112-61-5
6-methoxy-1-naphthoic acid

: 1338221-34-3
N-[3-benzyl-5-(4-methoxyphenyl)pyrazin-2-yl]-6-methoxy-N-(6-methoxy-1-naphthoyl)-1-naphthamide

Guidance literature:: Multi-step reaction with 2 steps

1: thionyl chloride / 3 h / Inert atmosphere; Reflux

2: dmap; pyridine / 18 h / 50 °C / Inert atmosphere

With pyridine; dmap; thionyl chloride;