(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

Base Information

Chemical Name:(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate
CAS No.:1353285-66-1
Molecular Formula:C₄₀H₇₄O₇Si₂
Molecular Weight:723.194
Hs Code.:

Synonyms:(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

Suppliers and Price of (3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

There total 1 articles about (3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 1009036-47-8
(2R,3S,4R,5S,6S,8R)-3,9-di(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoic acid

: 1198600-34-8
(3S,4R)-3-methylhex-1-ene-3,4-diol

: 1353285-66-1
(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

Guidance literature:: (2R,3S,4R,5S,6S,8R)-3,9-di(tert-butyldimethylsilanyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoic acid; With 2,4,6-trichlorobenzoyl chloride; triethylamine; In tetrahydrofuran; at 20 ℃; for 3h;

(3S,4R)-3-methylhex-1-ene-3,4-diol; With dmap; In benzene; at 20 ℃; for 15h;
DOI:10.1021/jo201158q

Reference yield: 78.0%

: 1353285-66-1
(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

: 1353285-68-3
(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3-(tert-butyldimethylsilyloxy)-9-hydroxy-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

Guidance literature:: With 10-camphorsufonic acid; In methanol; at 0 ℃; for 1h;
DOI:10.1021/jo201158q

Reference yield:

: 1353285-66-1
(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3,9-bis-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethylnonanoate

: 1353285-70-7
(3S,4R)-3-hydroxy-3-methylhex-1-en-4-yl (2R,3S,4R,5S,6S,8R)-3-(tert-butyldimethylsilyloxy)-5-(4-methoxybenzyloxy)-2,4,6,8-tetramethyl-9-oxononanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 10-camphorsufonic acid / methanol / 1 h / 0 °C

2: Dess-Martin periodane / dichloromethane / 0.5 h / 20 °C

With 10-camphorsufonic acid; Dess-Martin periodane; In methanol; dichloromethane;
DOI:10.1021/jo201158q