4-Chloro-2-methanesulfinyl-pyrimidine-5-carboxylic acid ethyl ester

Base Information

• Chemical Name: 4-Chloro-2-methanesulfinyl-pyrimidine-5-carboxylic acid ethyl ester
• CAS No.: 98490-76-7
• Molecular Formula: C₈H₉ClN₂O₄S
• Molecular Weight: 264.689
• Mol file: 98490-76-7.mol

Synonyms:4-chloro-2-methanesulfonyl-pyrimidine-5-carboxylic acid ethyl ester

Chemical Property of 4-Chloro-2-methanesulfinyl-pyrimidine-5-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Chloro-2-methanesulfinyl-pyrimidine-5-carboxylic acid ethyl ester

There total 2 articles about 4-Chloro-2-methanesulfinyl-pyrimidine-5-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester (5909-24-0) → 4-chloro-2-methanesulfonyl-pyrimidine-5-carboxylic acid ethyl ester (98490-76-7)

Guidance literature:

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester; With formic acid; dihydrogen peroxide; In dichloromethane; water; at 20 ℃; for 12h;

With sodium sulfite; In dichloromethane; water;

Reference yield:

→ 4-chloro-2-methanesulfonyl-pyrimidine-5-carboxylic acid ethyl ester (98490-76-7)

Guidance literature:

4-Chlor-2-methylmercapto-5-carbethoxy-pyrimidin, Chlor in 1percent wss. HCl (0-5grad, 5-10 Min.), NaHSO3;

DOI:10.1021/jo01077a015

Reference yield:

2,4-difluorophenol (367-27-1) + 4-chloro-2-methanesulfonyl-pyrimidine-5-carboxylic acid ethyl ester (98490-76-7) → 2-(2,4-difluoro-phenoxy)-4-hydrazino-pyrimidine-5-carboxylic acid ethyl ester (1033720-56-7)

Guidance literature:

2,4-difluorophenol; 4-chloro-2-methanesulfonyl-pyrimidine-5-carboxylic acid ethyl ester; With sodium ethanolate; In tert-butyl methyl ether; water; at 0 - 20 ℃; for 1h;

With hydrazine; In tert-butyl methyl ether; water; at 0 - 20 ℃; for 4h;

With water; In tert-butyl methyl ether;

upstream raw materials:

4-chloro-2-methanesulfanylpyrimidine-5-carboxylic acid ethyl ester

Downstream raw materials:

4-methylamino-2-methylsulfonyl-pyrimidine-5-carboxylic acid ethyl ester

2-(2,4-difluoro-phenoxy)-4-hydrazino-pyrimidine-5-carboxylic acid ethyl ester

Refernces