Ethyl 7-bromo-1H-indole-2-carboxylate

Base Information

Chemical Name:Ethyl 7-bromo-1H-indole-2-carboxylate
CAS No.:16732-69-7
Molecular Formula:C11H10BrNO2
Molecular Weight:268.11
Hs Code.:2933990090
DSSTox Substance ID:DTXSID30426911
Wikidata:Q72473239
Mol file:16732-69-7.mol

Synonyms:Ethyl 7-bromo-1H-indole-2-carboxylate;16732-69-7;Ethyl 7-bromoindole-2-carboxylate;7-Bromo-1H-indole-2-carboxylic acid ethyl ester;7-Bromoindole-2-carboxylic acid ethyl ester;7-Bromo-1H-indole-2-carboxylicacidethylester;1H-Indole-2-carboxylic acid, 7-bromo-, ethyl ester;MFCD04972046;sec-butylmethacrylate;SCHEMBL1301646;DTXSID30426911;FKIRSCKRJJUCNI-UHFFFAOYSA-N;BBL104283;CL3469;STL558483;AKOS005144075;AC-5215;CS-W004711;GS-6487;PB41177;SY040455;A3711;FT-0648929;EN300-71865;B-8730

Suppliers and Price of Ethyl 7-bromo-1H-indole-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl 7-bromo-1H-indole-2-carboxylate
500mg
$ 65.00

TRC
Ethyl 7-bromo-1H-indole-2-carboxylate
100mg
$ 45.00

Sigma-Aldrich
Ethyl 7-bromo-1H-indole-2-carboxylate
1g
$ 140.00

Matrix Scientific
Ethyl 7-bromoindole-2-carboxylate 95+%
1g
$ 39.00

Matrix Scientific
Ethyl 7-bromoindole-2-carboxylate 95+%
5g
$ 119.00

Matrix Scientific
Ethyl 7-bromoindole-2-carboxylate 95+%
25g
$ 415.00

Crysdot
Ethyl 7-bromo-1H-indole-2-carboxylate 98%
10g
$ 208.00

Chemenu
Ethyl 7-bromo-1H-indole-2-carboxylate 95%+
25g
$ 504.00

Chemenu
Ethyl 7-bromo-1H-indole-2-carboxylate 95%+
10g
$ 252.00

Biosynth Carbosynth
7-Bromo-1H-indole-2-carboxylic acid ethyl ester
500 mg
$ 115.00

Total 50 raw suppliers

Chemical Property of Ethyl 7-bromo-1H-indole-2-carboxylate

Chemical Property:

Vapor Pressure:1.94E-06mmHg at 25°C
Melting Point:85-86 °C(Solv: ethanol (64-17-5))
Refractive Index:1.646
Boiling Point:394.7 °C at 760 mmHg
PKA:13.35±0.30(Predicted)
Flash Point:192.5 °C
PSA：42.09000
Density:1.554 g/cm³
LogP:3.10710
Storage Temp.:Sealed in dry,Room Temperature
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:266.98949
Heavy Atom Count:15
Complexity:247

Purity/Quality:

99%, ^*data from raw suppliers

Ethyl 7-bromo-1H-indole-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=CC2=C(N1)C(=CC=C2)Br

Technology Process of Ethyl 7-bromo-1H-indole-2-carboxylate

There total 6 articles about Ethyl 7-bromo-1H-indole-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 617-35-6
2-oxo-propionic acid ethyl ester

: 16732-66-4
2-bromophenylhydrazine

: 16732-69-7
ethyl 7-bromo-1H-indole-2-carboxylate

Guidance literature:: With p-toluenesulfonic acid monohydrate; In toluene; Heating;
DOI:10.1021/jo062627r

Reference yield:

: 617-35-6
2-oxo-propionic acid ethyl ester

: 50709-33-6
2-bromophenylhydrazine hydrochloride

: 16732-69-7
ethyl 7-bromo-1H-indole-2-carboxylate

Guidance literature:: With toluene-4-sulfonic acid; In benzene; for 12h; Heating;
DOI:10.1021/jm0341047

Reference yield:

: 50709-33-6
2-bromophenylhydrazine hydrochloride

: 16732-69-7
ethyl 7-bromo-1H-indole-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydroxide / toluene / 1 h

2: toluene-4-sulfonic acid / toluene / 16 h / Reflux; Water separator

With sodium hydroxide; toluene-4-sulfonic acid; In toluene;