(E)-ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate

Base Information

• Chemical Name: (E)-ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate
• CAS No.: 18474-55-0
• Molecular Formula: C11H13 Br N2 O2
• Molecular Weight: 285.14
• Hs Code.: 2928000090
• Mol file: 18474-55-0.mol

Synonyms:Pyruvicacid, ethyl ester, (o-bromophenyl)hydrazone (6CI); Pyruvic acid, ethyl ester,2-[(o-bromophenyl)hydrazone] (8CI); o-Bromophenylhydrazone ethylmethylsuccinate

Chemical Property of (E)-ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate

Chemical Property:

• Melting Point: 78.5-79.5 °C
• Boiling Point: 337.3±44.0 °C(Predicted)
• PKA: 11.65±0.10(Predicted)
• PSA: 50.69000
• Density: 1.38±0.1 g/cm3(Predicted)
• LogP: 2.87300
• Storage Temp.: 2-8°C

Purity/Quality:

99.3% ^*data from raw suppliers

Ethyl2-(2-(2-bromophenyl)hydrazono)propanoate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (E)-ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate

There total 2 articles about (E)-ethyl 2-(2-(2-bromophenyl)hydrazono)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(2-bromo-phenylhydrazono)-propionic acid → 2-(2-bromo-phenylhydrazono)-propionic acid ethyl ester (18474-55-0)

Guidance literature:

With sulfuric acid;

Reference yield:

2-oxo-propionic acid ethyl ester (617-35-6) + 2-bromophenylhydrazine (16732-66-4) → 2-(2-bromo-phenylhydrazono)-propionic acid ethyl ester (18474-55-0)

Guidance literature:

In ethanol;

DOI:10.1139/v60-206

Reference yield:

2-(2-bromo-phenylhydrazono)-propionic acid ethyl ester (18474-55-0) → 7-bromo-1H-indole-2-carboxylic acid (16732-71-1)

Guidance literature:

Multi-step reaction with 2 steps

1: polyphosphoric acid

2: ethanolic alkaline solution

With PPA; alkaline solution;

upstream raw materials:

2-oxo-propionic acid ethyl ester

2-bromophenylhydrazine

Downstream raw materials:

ethyl 7-bromo-1H-indole-2-carboxylate

7-bromo-1H-indole

7-bromo-1H-indole-2-carboxylic acid